2234-82-4

Basic information

• Product Name: PROPYLMAGNESIUM CHLORIDE
• Synonyms: PropylMagnesiuM chloride, 2M solution in diethyl ether, AcroSeal;n-Propylmagnesium chloride 1M solution in THF;n-Propylmagnesium chloride 2M solution in DEE;PropylMagnesiuM chloride, 2.0M solution in diethyl ether, J&KSeal;PropylMagnesiuM chloride soluti;PropylMagnesiuM chloride, 2.0 M solution in diethyl ether, SpcSeal;n-Propylmagnesium chloride solution ;n-Propylmagnesium chloride solution, 1M in 2-MeTHF
• CAS NO: 2234-82-4
• Molecular Formula: C₃H₇ClMg
• Molecular Weight: 102.85
• EINECS: 218-785-5
• Product Categories: Grignard Reagent;AlkylChemical Synthesis;Grignard Reagents;Organic Bases;Organometallic Reagents;Synthetic Reagents
• Mol File: 2234-82-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 148-150 °C(Press: 15 Torr)
• Flash Point: −40 °F
• Appearance: /
• Density: 0.83 g/mL at 20 °C
• Water Solubility: Reacts with water.
• Sensitive: Air & Moisture Sensitive
• BRN: 3600246
• CAS DataBase Reference: PROPYLMAGNESIUM CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: PROPYLMAGNESIUM CHLORIDE(2234-82-4)
• EPA Substance Registry System: PROPYLMAGNESIUM CHLORIDE(2234-82-4)

Safety Data

• Hazard Codes: F+,C,F
• Statements: 12-14/15-22-34-66-67-19-11
• Safety Statements: 16-26-36/37/39-43-45-7/8
• RIDADR: UN 3399 4.3/PG 1
• WGK Germany: 1
• TSCA: Yes
• HazardClass: 4.3
• Hazardous Substances Data: 2234-82-4(Hazardous Substances Data)

Usage

Chemical Properties

Dark brown liquid

Uses

Different sources of media describe the Uses of 2234-82-4 differently. You can refer to the following data:
1. Propylmagnesium Chloride is a useful reagent for the preparation of 4-(2,4-bis(2-Hydroxyphenyl)-1H-imidazol-1-yl)benzoic Acid derivatives as novel iron chelators.
2. Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF)2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

General Description

This product, 1.0 M in 2-methyltetrahydrofuran aligns with Safer Solvents and Auxiliaries, Use of Renewable Feedstocks and Inherently Safer Chemistry for Accident Prevention.

InChI:InChI=1/C3H7.ClH.Mg/c1-3-2;;/h1,3H2,2H3;1H;/q;;+1/p-1/rC3H7ClMg/c1-2-3-5-4/h2-3H2,1H3

Upstream product

• 540-54-5 1-Chloropropane 

Downstream Products

• 123-72-8 butyraldehyde 
• 464-07-3 3,3-dimethyl-2-butanol 
• 5340-41-0 2,2,3-trimethyl-hexan-3-ol 
• 717909-06-3 3-phenyl-1-piperidino-hexan-3-ol 
• 66225-17-0 4-methyl-hept-2-ene 
• 74-98-6 propane 
• 412016-63-8 4-aminomethyl-heptan-4-ol 
• 102162-55-0 3-benzyl-3-hydroxy-2-phenyl-hexanoic acid 
• 1116-61-6 tripropylborane 
• 2234-97-1 tris-n-propylphosphine 
• 998-29-8 tripropylsilane 
• 17841-51-9 hexapropyl-disiloxane 
• 5905-48-6 dipropylcadmium 
• 3015-98-3 Indium-tripropyl 

Relevant articles and documents

Alkynyl halide compounds and alkenyl acetate compounds therefrom

The invention provides a novel method for the synthetic preparation of an ω-haloalkyne compound of the general formula R--C C--CH2)n X, in which X is a halogen atom, R is a monovalent hydrocarbon group and n is 4, 5 or 6, by the coupling reaction of a Grignard reagent RMgX' and an ω-halo-1-bromoalkyne compound of the formula X--CH2)n C C-Br. The ω-haloalkyne compound obtained in the above can be readily converted to the corresponding alkenyl acetate of the formula R--CH=CH--CH2)n OCOCH3 by first acetylating and then partially hydrogenating in the presence of a Lindlar catalyst. In particular, 7, 11-hexadecadienyl acetate, which is a sexual pheromone compound of a noxious insect, is obtained in the same route of synthesis starting with the Grignard reagent of a 1-halo-3-octene and 1, 8-dibromo-1-octyne.

Unsaturated vitamin E intermediates--dehydro and didehydro α-tocopherols

New dehydrotocopherols, namely cis- and trans- 3',4'-dehydrotocopherol; cis- and trans- 4',5'-dehydrotocopherol; and 4',4'-a-dehydrotocopherol, and new didehydrotocopherols, namely cis- and trans- 3',4'-11',12'-didehydrotocopherol; cis- and trans- 4',5'-11',12'-didehydrotocopherol; and 4',4'a-11',12'-didehydrotocopherol, are useful intermediates in the preparation of Vitamin E. These intermediates are prepared by reacting trimethylhydroquinone under acid catalysis with certain C20 intermediates, namely: STR1 where R represnts a 3,7-dimethyloctyl or a 3,7-dimethyl-6-octenyl radical and X is halogen, hydroxyl, acetate, C1-4 alkanoate, C3-4 alkenoate, aralkenoate and benzoate.