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143679-80-5

(1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID is a white powder chemical compound that serves as a crucial building block in the synthesis of helical foldamers, which are complex and versatile molecular structures with potential applications in various fields.

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  • 143679-80-5 Structure

  • Basic information

    1. Product Name: (1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID
    2. Synonyms: (1S,2S)-BOC-ACPC;(1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID;(1S:2S)-BOC-2-AMINO-1-CYCLOPENTANE CARBOXYLIC ACID;(1S,2S)-Boc-aminocyclopentane carboxylic acid;(1S,2S)-2-(tert-butoxycarbonylaMino)cyclopentanecarboxylic acid;(1S-trans)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopentanecarboxylic acid;Cyclopentanecarboxylicacid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (1S,2S)-;Trans-(1S,2S)-2-((tert-butoxycarbonyl)aMino)cyclopentanecarboxylic acid
    3. CAS NO:143679-80-5
    4. Molecular Formula: C11H19NO4
    5. Molecular Weight: 229.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 143679-80-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.15
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: (1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID(143679-80-5)
    11. EPA Substance Registry System: (1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID(143679-80-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 143679-80-5(Hazardous Substances Data)

143679-80-5 Usage

Uses

Used in Pharmaceutical Industry:
(1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID is used as a building block for the synthesis of helical foldamers, which are essential in the development of novel pharmaceutical compounds. These foldamers can be engineered to target specific biological receptors or enzymes, potentially leading to the creation of more effective and selective drugs.
Used in Chemical Research:
In the field of chemical research, (1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID is used as a key component in the study and development of helical foldamers. These molecules can provide insights into the structure and function of biological systems, as well as contribute to the advancement of materials science and nanotechnology.
Used in Material Science:
(1S,2S)-BOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID is used as a building block for the creation of helical foldamers, which can be utilized in the development of new materials with unique properties. These materials may have potential applications in areas such as electronics, sensors, and energy storage.

Check Digit Verification of cas no

The CAS Registry Mumber 143679-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,6,7 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 143679-80:
(8*1)+(7*4)+(6*3)+(5*6)+(4*7)+(3*9)+(2*8)+(1*0)=155
155 % 10 = 5
So 143679-80-5 is a valid CAS Registry Number.

143679-80-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,2S)-2-((tert-Butoxycarbonyl)amino)cyclopentanecarboxylic acid

1.2 Other means of identification

Product number -
Other names (1S,2S)-Boc-Acpc

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143679-80-5 SDS

143679-80-5Relevant articles and documents

(S,S)-trans-cyclopentane-constrained peptide nucleic acids. A general backbone modification that improves binding affinity and sequence specificity

Pokorski, Jonathan K.,Witschi, Mark A.,Purnell, Bethany L.,Appella, Daniel H.

, p. 15067 - 15073 (2007/10/03)

Replacing the ethylenediamine portion of aminoethylglycine peptide nucleic acids (aegPNAs) with one or more (S,S)-trans-cyclopentane diamine units significantly increases binding affinity and sequence specificity to complementary DNA, making these modifie

Synthesis of enantiomerically pure cis and trans 2-aminocyclopentanecarboxylic acids. Use of proline replacements in potential HIV-protease inhibitors

Noeteberg, Daniel,Branalt, Jonas,Kvarnstroem, Ingemar,Classon, Bjoern,Samuelsson, Bertil,Nillroth, Ulrika,Danielson, U. Helena,Karlen, Anders,Hallberg, Anders

, p. 7975 - 7984 (2007/10/03)

The synthesis of the four diastereomeric 2-aminocyclopentanecarboxylic acids, their use as replacements for proline in potential HIV protease inhibitors containing a hydroxyethylamine dipeptide isostere and the evaluation of the biological activity of these is described.

Analogs of Ac-CCK-7 Incorporating Dipeptide Mimics in Place of Met28-Gly29

Tilley, Jefferson W.,Danho, Waleed,Shiuey, Shian-Jun,Kulesha, Irina,Swistok, Joseph,et al.

, p. 3774 - 3783 (2007/10/02)

A series of analogs of Ac-CCK-7 28-Gly29-Trp-Met-Asp-Phe-NH2, (1)> were prepared in which The Met28-Gly29 dipeptide was replaced by ω-aminoalkanoic acids.Compounds were assessed in binding assay

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