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DMT-2'-F-dGiBu is a chemical compound that is a modification of the psychedelic substance DMT (N,N-Dimethyltryptamine). It is a tryptamine derivative known for its hallucinogenic effects, producing profound alterations in perception, mood, and cognition. DMT-2'-F-dGiBu features a fluoro substitution at the 2' position of the indole ring and a butyl group attached to the dimethylamine moiety, which is thought to enhance the potency and duration of the psychoactive effects of DMT.

144089-96-3

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144089-96-3 Usage

Uses

Used in Psychedelic Research:
DMT-2'-F-dGiBu is used as a research chemical for studying the effects of DMT on the brain and consciousness. Its enhanced potency and duration of psychoactive effects make it a valuable tool for investigating the mechanisms of action and potential therapeutic applications of psychedelic substances.
Used in Pharmaceutical Development:
DMT-2'-F-dGiBu has the potential to be developed into a pharmaceutical drug for the treatment of various mental health conditions. Its unique properties and effects on perception, mood, and cognition may offer new avenues for the development of novel therapeutic agents.
Used in Spiritual and Personal Growth Practices:
DMT-2'-F-dGiBu, like other psychedelic substances, may be used in spiritual and personal growth practices to explore consciousness, enhance self-awareness, and facilitate personal transformation. Its profound effects on perception and cognition can provide users with unique insights and experiences that may contribute to personal development and spiritual growth.

Check Digit Verification of cas no

The CAS Registry Mumber 144089-96-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,0,8 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 144089-96:
(8*1)+(7*4)+(6*4)+(5*0)+(4*8)+(3*9)+(2*9)+(1*6)=143
143 % 10 = 3
So 144089-96-3 is a valid CAS Registry Number.

144089-96-3Downstream Products

144089-96-3Relevant articles and documents

2′-Fluoro-c-di-GMP as an oral vaccine adjuvant

Li, Jia,Lee, Rhonda Kuo,Chen, Wangxue,Yan, Hongbin

, p. 41481 - 41489 (2019)

Bis-(3′-5′)-cyclic dimeric 2′-deoxy-2′-fluoroguanosine monophosphate (2′-F-c-di-GMP) was synthesized through the modified H-phosphonate chemistry. Oral immunization of C57BL/6 mice with Helicobacter pylori cell-free sonicate extract adjuvanted with 2′-F-c

COMPOSITIONS AND METHODS FOR ACTIVATING "STIMULATOR OF INTERFERON GENE"-DEPENDENT SIGNALLING

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Paragraph 00492; 00493, (2017/05/17)

The present invention provides highly active cyclic-di-nucleotide (CDN) immune stimulators that activate DCs via a recently discovered cytoplasmic receptor known as STING (Stimulator of Interferon Genes). In particular, the CDNs of the present invention are provided in the form of a composition comprising one or more cyclic purine dinucleotides induce human STING-dependent type I interferon production, wherein the cyclic purine dinuclotides present in the composition are 2'- or 3'-mono-fluoro substituted, or 2'3'-di-fluoro substituted mixed linkage 2',5' - 3',5' CDNs.

COMPOSITIONS AND METHODS FOR ACTIVATING "STIMULATOR OF INTERFERON GENE" -DEPENDENT SIGNALLING

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Paragraph 00383; 00384, (2016/09/26)

The present invention provides highly active cyclic-di-nucleotide (CDN) immune stimulators that activate DCs via a recently discovered cytoplasmic receptor known as STING (Stimulator of Interferon Genes), In particular, the CDNs of the present invention a

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Kawasaki,Casper,Freier,Lesnik,Zounes,Cummins,Gonzalez,Cook

, p. 831 - 841 (2007/10/02)

'Uniformly' modified phosphodiester or phosphorothioate oligonucleotides incorporating 2'-deoxy-2'-fluoroadenosine, -guanosine, -uridine, and - cytidine, reported herein for the first time, when hybridized with RNA afforded consistent additive enhancement of duplex stability without compromising base-pair specificity. CD spectra of the 2'-deoxy-2'-fluoro- modified oligonucleotides hybridized with RNA indicated that the duplex adopts a fully A-form conformation. The 2'-deoxy-2'-fluoro-modified oligonucleotides in phosphodiester form were not resistant to nucleases; however, the modified phosphorothioate oligonucleotides were highly nuclease resistant and retained exceptional binding affinity to the RNA targets. The stabilizing effects of the 2'-deoxy-2'-fluoro modifications on RNA-DNA duplexes were shown to be superior to those of the 2'-O-methylribo substitutions. RNA hybrid duplexes with uniformly 2'-deoxy-2'-fluoro-modified oligonucleotides did not support HeLa RNase H activity; however, incorporation of the modifications into 'chimeric' oligonucleotides has been shown to activate mammalian RNase H. 'Uniformly' modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides afforded antisense molecules with (1) high binding affinity and selectivity for the RNA target and (2) stability toward nucleases.

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