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N-Methylthiazole-2-methanamine, also known as MTMA, is a chemical compound with the molecular formula C5H8N2S. It is a thiazole derivative known for its unique structure, making it a versatile building block in chemical synthesis. MTMA can undergo various reactions, such as alkylation and acylation, to form different compounds with diverse applications. Its potential biological activities and pharmacological properties are also being studied, indicating its potential for various industrial and therapeutic applications.

144163-68-8

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144163-68-8 Usage

Uses

Used in Pharmaceutical Synthesis:
N-Methylthiazole-2-methanamine is used as an intermediate in the synthesis of pharmaceuticals and organic compounds. Its unique structure allows it to be a versatile building block, enabling the creation of various compounds with different therapeutic properties.
Used in Chemical Synthesis:
In the chemical synthesis industry, N-Methylthiazole-2-methanamine is used as a versatile intermediate. Its ability to undergo reactions such as alkylation and acylation makes it suitable for the production of a wide range of compounds with diverse applications.
Used in Research and Development:
MTMA is utilized in research and development for its potential biological activities and pharmacological properties. Its unique structure and reactivity make it a promising candidate for the discovery of new therapeutic agents and other applications in the scientific community.

Check Digit Verification of cas no

The CAS Registry Mumber 144163-68-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,1,6 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 144163-68:
(8*1)+(7*4)+(6*4)+(5*1)+(4*6)+(3*3)+(2*6)+(1*8)=118
118 % 10 = 8
So 144163-68-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H8N2S/c1-6-4-5-7-2-3-8-5/h2-3,6H,4H2,1H3

144163-68-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-methyl-1-(1,3-thiazol-2-yl)methanamine

1.2 Other means of identification

Product number -
Other names METHYL-THIAZOL-2-YLMETHYL-AMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144163-68-8 SDS

144163-68-8Relevant articles and documents

Total synthesis of micromide: A marine natural product

Han, Jianrong,Lian, Jingtang,Tian, Xia,Zhou, Shengwei,Zhen, Xiaoli,Liu, Shouxin

, p. 7232 - 7238 (2015/02/19)

This paper describes an efficient procedure for the synthesis of micromide, a natural product that shows anti-solid-tumor activity. Our strategy involved the synthesis of N-nosyl-protected amino acids and their N-methylation with iodo-methane. The hindered oligopeptides containing N-methyl amino acids were synthesized in excellent yields and high purities.[ampi]]

SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS

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Page/Page column 99; 117, (2009/12/05)

This invention relates to a new sordarin derivative or a pharmaceutically acceptable salt thereof, which has antimicrobial activities (especially, antifungal activities), to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases in a human being or an animal.

CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION

-

Page/Page column 81, (2008/06/13)

The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administ

Symmetry-Based Inhibitors of HIV Protease. Structure-Activity Studies of Acylated 2,4-Diamino-1,5-diphenyl-3-hydroxypentane and 2,5-Diamino-1,6-diphenylhexane-3,4-diol

Kempf, Dale J.,Codacovi, Lynnmarie,Wang, Xiu Chun,Kohlbrenner, William E.,Wideburg, Norman E.,et al.

, p. 320 - 330 (2007/10/02)

The structure-activity relationships in two series of novel, symmetry-based inhibitors of HIV protease, the enzyme responsible for maturation of the human immunodeficiency virus, are described.Beginning with lead compounds 3-6, the effect of adding polar, heterocyclic end groups to one or both ends of the symmetric or pseudosymmetric inhibitors was probed.Aqueous solubility was enhanced >1000-fold while maintaining potent inhibition of purified HIV-1 protease and anti-HIV activity in vitro.Pharmacokinetic studies in rats indicated a substantial difference in the absorption properties of mono-ol-based and diol-based inhibitors.The oral bioavailability of inhibitor 19 in rats was 19percent; however, the Cmax obtained failed to exceed the anti-HIV EC50 in vitro.Substantial plasma levels of potent inhibitors of the diol class were not obtained after oral administration in rats; however, the optimal combination of aqueous solubility and in vitro antiviral activity of several inhibitors support their potential use in intravenous therapy.

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