14447-02-0

Basic information

• Product Name: dipropyl but-2-ynedioate
• Synonyms: 2-butynedioic acid, dipropyl ester; Dipropyl but-2-ynedioate
• CAS NO: 14447-02-0
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.2158
• Mol File: 14447-02-0.mol

Chemical Properties

• Boiling Point: 285.8°C at 760 mmHg
• Flash Point: 122.1°C
• Density: 1.078g/cm³
• Vapor Pressure: 0.00274mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: dipropyl but-2-ynedioate(CAS DataBase Reference)
• NIST Chemistry Reference: dipropyl but-2-ynedioate(14447-02-0)
• EPA Substance Registry System: dipropyl but-2-ynedioate(14447-02-0)

Safety Data

• Hazardous Substances Data: 14447-02-0(Hazardous Substances Data)

Upstream product

• 71-23-8 propan-1-ol 
• 142-45-0 Acetylenedicarboxylic acid 
• 419561-47-0 dipropyl (E)-2,3-dibromobut-2-enedioate 

Downstream Products

• 17261-24-4 5-phenylindeno<2,1-a>indene 
• 138408-23-8 dipropyl (Z)-2-(10-phenylindeno<2,1-a>inden-5-yl)-2-butendioate 
• 56366-00-8 Benzene-1,2,3,4,5,6-hexacarboxylic acid hexapropyl ester 
• 172537-92-7 dipropyl 2,2-dicarbonyl-2-(η(5)-cyclopentadienyl)-1,1-diphenyl-3-(2,4,6-trimethylphenyl)-1λ(4),3-diphospha-2-molybda-4-cyclopentene-4,5-dicarboxylate 

Relevant articles and documents

Propeller-Shaped D3h-Symmetric Macrocycles with Three 1,8-Diazaanthracene Blades as Building Blocks for Photochemically Induced Growth Reactions

The efficient synthesis of new D3h-symmetric propeller-shaped, double-decker compounds with three vertically standing diazaanthracene units arranged so as to allow for photochemically induced intermolecular growth reaction by [4+4] cycloaddition is presented. The propellers bear alkyl chains of four different lengths (ethyl, propyl, hexyl, dodecyl) to have flexibility in creating ordered arrays by packing them into single crystals, onto solid substrates or into mesophases. All propellers are obtained in only six steps and on a 50-200 mg scale. The sequence passes through the ditriflated 1,8-diazaanthracene derivatives 6 which are a very versatile building block for many purposes and were therefore synthesized on a 30 g scale. A new class of propeller-shaped macrocycles is accessible via a six-step procedure with overall yields ranging from 6-16%. These cyclophanes are equipped with 1,8-diazaanthracene units and are designed for photochemical growth reactions in two dimensions.

A 2- fluoro fumaric acid ester (formula I) and its preparation method and application

The invention discloses 2-fuloro fumarate (formula I) and a preparation method thereof. Experiments show that: the kinds of compounds are capable of effectively inhibiting NF-kB transcriptional activity introduced by TNF-alpha, and further are capable of treating diseases introduced by NF-kB, such as psoriasis, multiple sclerosis, arthritis, eye inflammation or allergy, asthma and lupus erythematosus, and can be used as an immunosuppressant for organ transplantation.

Photochemical synthesis of prochiral dialkyl 3,3-dialkylcyclopropene-1,2-dicarboxylates with facial shielding substituents and related substrates

Different types of cyclopropene-1,2-dicarboxylates 1 have been obtained by photochemical methods from the corresponding pyrazoles 11, 12, or 13. These pyrazoles were synthesized by 1,3-dipolar cycloadditions of alkynes 8 or 9 with either preformed diazoalkanes or diazoalkanes generated photochemically in situ, by use of oxadiazolines as diazoalkane precursors. The numerous substrates have clearly established the scope and limitations of the syntheses of the precursors and the cyclopropenes by the different routes; even prochiral and enantiomerically pure chiral derivatives could be synthesized. Numerous precursors and cyclopropenes could be characterized by X-ray crystal structure analyses, which revealed interesting structural features and allowed unequivocal assignment of different diastereomers or constitutional isomers. Some of the photochemical reactions produced unique side-products; the crystal structure analyses were absolutely crucial for unambiguous structural assignment here. Wiley-VCH Verlag GmbH, 2001.