Site-specific incorporation of non-natural residues into peptides: Effect of residue structure on suppression and translation efficiencies
A systematic survey of the structural requirements for biosynthetic incorporation of non-natural residues into a polypeptide is presented. Relative translation efficiencies for a series of 12 semi-synthetic acylated suppressor tRNAs ranged from 0 to 91% depending on the structure of the residue incorporated.
Bain,Wacker, Dean A.,Kuo, Eric E.,Chamberlin, A. Richard
p. 2389 - 2400
(2007/10/02)
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