Enantioselective chlorocyclization of indole derived benzamides for the synthesis of spiro-indolines
(DHQD)2PHAL catalyzed enantioselective chlorocyclization of indole derived benzamides was realized. Spiro-indolines containing a continuous quaternary carbon center and tertiary carbon center were obtained in good yields with excellent enantioselectivity (up to 90% yield and 96% ee).
Yin, Qin,You, Shu-Li
p. 4266 - 4269
(2013/09/12)
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