Development of one-pot synthesis of α-hydroxy α-trifluoromethyl amides
An efficient one-pot-three-step method has been developed to assemble readily available aryl or heteroaryl halides, methyl trifluoropyruvate, and amines into biologically important α-hydroxy α-trifluoromethyl amides without isolation of any intermediates.
Meng, Zhaoyang,Butcher, William E.
p. 5133 - 5136
(2013/08/28)
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