145157-87-5 Usage
Uses
Used in Polymer and Plastics Industry:
4-Amino-4'-tert butyl diphenyl ether is used as a stabilizer in the manufacturing process of polymers and plastics. It helps to prevent degradation and improve the durability of these materials, ensuring their longevity and performance.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4-Amino-4'-tert butyl diphenyl ether serves as an essential intermediate in the synthesis of various drugs. Its unique structure allows for the development of new medicinal compounds with potential therapeutic applications.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical sector, this compound is utilized in the synthesis of pesticides and other agricultural chemicals. Its role in creating effective and safe agrochemicals contributes to enhanced crop protection and yield.
Used as an Antioxidant:
4-Amino-4'-tert butyl diphenyl ether can act as an antioxidant in various industrial applications. Its ability to neutralize harmful free radicals helps to prevent oxidation and maintain the quality and stability of products.
Used as an Ultraviolet Absorber:
4-AMINO-4'-TERT BUTYL DIPHENYL ETHER also functions as an ultraviolet (UV) absorber, protecting materials from the damaging effects of UV radiation. It is particularly useful in applications where exposure to sunlight or other UV sources is common, such as in coatings, adhesives, and sealants.
Safety Precautions:
It is crucial to handle 4-Amino-4'-tert butyl diphenyl ether with care, as it can be harmful if ingested or inhaled. Additionally, it may cause skin and eye irritation upon contact, necessitating the use of appropriate personal protective equipment during its handling and application.
Check Digit Verification of cas no
The CAS Registry Mumber 145157-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,5 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 145157-87:
(8*1)+(7*4)+(6*5)+(5*1)+(4*5)+(3*7)+(2*8)+(1*7)=135
135 % 10 = 5
So 145157-87-5 is a valid CAS Registry Number.
145157-87-5Relevant articles and documents
Synthesis of N-Substituted Iminosugar Derivatives and Evaluation of Their Immunosuppressive Activities
Lv, Zhuo,Song, Chengcheng,Niu, Youhong,Li, Qin,Ye, Xin-Shan
, p. 338 - 351 (2018/02/27)
It is important to find more effective and safer immunosuppressants, because clinically used immunosuppressive agents have significant side effects. A series of N-substituted iminosugar derivatives were designed and synthesized, and their immunosuppressive effects were evaluated by the CCK-8 assay. The results revealed that iminosugars 10 e and 10 i, that is, (3R,4S)-1-(4-heptyloxylphenylethyl)pyrrolidine-3,4-diol and (3R,4S)-1-[2-(2-chloro-4-(p-tolylthio)-phenyl-1-yl)ethyl]pyrrolidine-3,4-diol, respectively, exhibited the strongest inhibitory effects on mouse splenocyte proliferation (IC50=2.16 and 2.48 μm, respectively), whereas the iminosugars containing an amide group near the hydrophilic head (compounds 10 j–n) exhibited no inhibitory effects. Further studies revealed that the inhibitory effects on splenocyte proliferation may have come from the suppression of both IFN-γ and IL-4 cytokines. Our results suggest that synthetic iminosugars, especially compounds 10 e and 10 i, hold potential as immunosuppressive agents.
A focused library of protein tyrosine phosphatase inhibitors
Comeau, Anthony B.,Critton, David A.,Page, Rebecca,Seto, Christopher T.
supporting information; experimental part, p. 6768 - 6772 (2010/11/18)
Protein tyrosine phosphatases such as PTP1B and YopH are potential targets for the development of therapeutic agents against a variety of pathological conditions including diabetes, obesity, and infection by the bacterium Yersinia pestis. A focused library of bidentate α-ketoacid-based inhibitors has been screened against several tyrosine phosphatases. Compound 2a has IC 50 values of 43 and 220 nM against YopH and PTP1B, respectively, and shows a 30-fold selectivity for PTP1B over the closely related phosphatase TCPTP.
