The Potential of Carbocyclic Nucleosides for the Treatment of Aids: Synthesis of Some Diphosphorylphosphonates Possessing Potent Activity Against HIV-Coded Reverse Transcriptase
The phosphonates 19, 20, 24, 27 and the diphosphorylphosphonates 10 and 11 have been prepared as mimics of nucleoside-phosphates and -triphosphates respectively.The compounds 10 and 11 were found to be potent inhibitors of human immunodeficiency virus rev
Coe, Diane M.,Roberts, Stanley M.,Storer, Richard
p. 2695 - 2704
(2007/10/02)
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