145628-72-4Relevant articles and documents
Correction: Green synthesis of 1,4-benzodiazepines over La2O3 and La(OH)3 catalysts: Possibility of Langmuir–Hinshelwood adsorption (RSC Advances (2016) 6 (103455-103462) DOI: 10.1039/C6RA22719H)
, p. 4976 - 4978 (2018)
The authors regret that in the original manuscript there were some errors in the structures displayed in Scheme 1 and Table 1. The correct scheme and table are presented herein. (Figure Presented) The Royal Society of Chemistry apologises for these errors
Organocatalytic Green Approach Towards the Fabrication of Fused Benzo N,N-containing Heterocycles Facilitated by Ultrasonic Irradiation
Nongrum, Ridaphun,Kharmawlong, George Kupar,Rani, Jims World Star,Rahman, Noimur,Dutta, Arup,Nongkhlaw, Rishanlang
, p. 2873. (2019/08/26)
The development of a metal-free protocol for transformations in organic synthesis offers a significant potential environmental benefit. This article reports the exploration of meglumine, a nontoxic and biodegradable amino sugar, as an organocatalyst for the synthesis of biologically active 1H-dibenzo[b,e][1,4]diazepin-1-ones, highly regioselective benzimidazole derivatives and derivatives of quinoxalines. Operational simplicity, mild reaction conditions, shorter reaction times, and use of green solvents are the highlights of this protocol. The advantage of ultrasonic irradiation has been significantly explored for the synthesis of the aforesaid compounds. Furthermore, the multifaceted use of o-phenylenediamine has also been accentuated in the study.
Silica-supported NiO nanocomposites prepared: Via a sol-gel technique and their excellent catalytic performance for one-pot multicomponent synthesis of benzodiazepine derivatives under microwave irradiation
Nasir, Zeba,Ali, Abad,Shakir, Mohammad,Wahab, Rizwan,Shamsuzzaman,Lutfullah
, p. 5893 - 5903 (2017/07/11)
Heterogeneous and versatile NiO-SiO2 NCs were synthesized by a sol-gel technique and used as a catalyst for the one-pot multicomponent synthesis of benzodiazepine derivatives (4a-u) from a mixture of o-phenylenediamine, aromatic aldehydes and d
"on water" synthesis of dibenzo-[1,4]-diazepin-1-ones using l-proline as an organocatalyst and under catalyst-free conditions, and their evaluation as α-glucosidase inhibitors
Nagaraju, Sakkani,Perumal, Onkara P.,Divakar,Paplal, Banoth,Kashinath, Dhurke
supporting information, p. 8993 - 9001 (2017/08/29)
Functionalized dibenzo-[1,4]-diazepin-1-ones were synthesized using the "on-water" concept in the presence of l-proline (organocatalyst; 20 mol%) and under catalyst free conditions (sealed tube) in an aqueous medium. The resulting molecules were tested (i
Design, preparation and characterization of Cu/GA/Fe3O4@SiO2 nanoparticles as a catalyst for the synthesis of benzodiazepines and imidazoles
Shaabani, Ahmad,Sepahvand, Heshmatollah,Hooshmand, Seyyed Emad,Borjian Boroujeni, Mahmoud
, p. 414 - 421 (2016/05/19)
The synthesis and characterization of an efficient and reusable nanocatalyst, Cu/GA/Fe3O4@SiO2, obtained by ultrasonic-assisted grafting of guanidineacetic acid on modified Fe3O4@SiO2 core-shell nanocomposite spheres and subsequent immobilization of Cu(II), are described. The catalyst was characterized by means of X-ray diffraction, scanning and transmission electron microscopies, energy-dispersive X-ray spectroscopy, elemental analysis, thermogravimetric analysis, Fourier transform infrared spectroscopy, vibrating sample magnetometry and inductively coupled plasma optical emission spectrometry. The prepared nanocatalyst facilitated an efficient and straightforward friendly procedure for the synthesis of benzodiazepines and imidazoles in ethanol and under solvent-free conditions, respectively. The nanocatalyst can be easily recovered using a magnet and reused several times without any significant loss of activity.
Practical carbocatalysis by graphene oxide nanosheets in aqueous medium towards the synthesis of diversified dibenzo[1,4]diazepine scaffolds
Kausar, Nazia,Mukherjee, Prasun,Das, Asish R.
, p. 88904 - 88910 (2016/09/28)
GO nanosheets are found to be an efficient recyclable carbocatalyst for the construction of diversified dibenzo[1,4]diazepine nuclei starting from o-phenylenediamine, various aldehyde/ketone and 1,3-diketo compounds in aqueous medium. This new metal free
Investigation of the products of interaction of cyclic diketones with nitrogen-containing 1,4-binucleophiles
Kolos,Yurchenko,Orlov,Shishkina,Shishkin
, p. 1550 - 1559 (2007/10/03)
The interaction of arylbis(5,5-dimethylcyclohexane-1,3-dion-2-yl)methanes with o-phenylenediamine and o-aminophenol leads to the preparation of 3,3-dimethyl-11-aryl-2,3,4,5,10,11-hexahydrobenzo[b,e]-1,4-diazepin-1-ones and 3,3,6,6-tetramethyl-9-aryl-10-(2
NOVEL SYNTHESES OF HETEROCYCLES WITH N-(1-HALOALKYL)AZINIUM HALIDES: PART 6. PREPARATION OF 2,3,4,5,10,11-HEXAHYDRO-1H-DIBENZODIAZEPIN-1-ONES
Eynde, J. -J. Vanden,Mayence, A.,Maquestiau, A.,Anders E.
, p. 801 - 806 (2007/10/02)
Conversion of aldehydes into N-(1-chloroalkyl)pyridinium chlorides (by means of pyridine and thionyl chloride) and further reaction with 3-(2-aminophenyl)amino-5,5-dimethyl-2-cyclohexenone provide a novel and efficient route to the title compounds.
