145790-51-8

Basic information

• Product Name: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID
• Synonyms: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID
• CAS NO: 145790-51-8
• Molecular Formula: C₂₄H₃₃NO₅Si
• Molecular Weight: 443.60802
• Mol File: 145790-51-8.mol

Chemical Properties

• Boiling Point: 534 °C at 760 mmHg
• Flash Point: 276.7 °C
• Appearance: /
• Density: 1.12 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID(145790-51-8)
• EPA Substance Registry System: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID(145790-51-8)

Safety Data

• Hazardous Substances Data: 145790-51-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID is used as a key intermediate in the synthesis of peptide-based drugs for various therapeutic applications. Its role in protecting the functional groups of aspartic acid allows for the controlled assembly of complex peptide structures, enhancing the development of innovative medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID is utilized as a valuable tool for studying the structure-activity relationships of peptide molecules. This understanding is essential for optimizing the pharmacological properties of peptide drugs, such as potency, selectivity, and stability.
Used in Drug Development:
(S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID is employed in the development of new drugs, particularly in the design and synthesis of peptide therapeutics. Its protective groups enable the synthesis of peptides with specific functionalities and biological activities, contributing to the advancement of targeted and effective treatments for various diseases.

Upstream product

• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 59524-02-6 N-tert-butoxycarbonyl-L-serine benzyl ester 
• 145790-48-3 N-tert-Butoxycarbonyl-O-(tert-butyldiphenylsilyl)-L-serine Benzyl Ester 

Downstream Products

• 867326-58-7 [1-(tert-butyl-diphenyl-silanyloxymethyl)-2-imidazol-1-yl-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 873065-67-9 C₂₉H₃₉NO₆Si 
• 1430098-18-2 C₄₉H₅₈N₄O₉Si 
• 1430098-17-1 C₄₀H₄₈N₂O₆Si 
• 873065-74-8 C₂₉H₄₁NO₆Si 
• 702702-09-8 (2S)-2-(N-tert-butyloxycarbonyl)-amino-1-tert-butyldiphenylsilyloxy-4-diazo-heptan-3-one 
• 702702-13-4 (2S,3S,4R)-N-(tert-butyloxycarbonyl)-2-(tert-butyldiphenylsilyloxymethyl)-4-propyl-azetidin-3-ol 
• 702702-10-1 (2S,4R)-N-(tert-butyloxycarbonyl)-2-(tert-butyldiphenylsilyloxymethyl)-4-propyl-azetidin-3-one 
• 702702-14-5 (2S,3S,4R)-N-(tert-butyloxycarbonyl)-2-hydroxymethyl-4-propyl-azetidin-3-ol 
• 867326-60-1 [1-(tert-butyl-diphenyl-silanyloxymethyl)-2-(dimethyl-phenyl-silanyl)-allyl]-carbamic acid tert-butyl ester 
• 867326-59-8 [1-(tert-butyl-diphenyl-silanyloxymethyl)-2-(dimethyl-phenyl-silanyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester 

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