145934-65-2

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2,3-diMethyl-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2,3-diMethyl-;5-bromo-2,3-dimethyl-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 145934-65-2
• Molecular Formula: C9H9BrN2
• Molecular Weight: 225.08516
• Mol File: 145934-65-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2,3-diMethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2,3-diMethyl-(145934-65-2)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2,3-diMethyl-(145934-65-2)

Safety Data

• Hazardous Substances Data: 145934-65-2(Hazardous Substances Data)

Usage

Structure

Pyrrolopyridine derivative with a bromine atom at the 5-position and two methyl groups at the 2 and 3 positions

Type

Organic compound

Usage

Building block in the synthesis of pharmaceuticals and agrochemicals

Pharmacological properties

Potential as an antiviral and antifungal agent

Electronic applications

Investigated for use in organic light-emitting diodes (OLEDs) and other electronic applications due to its electron transport properties

Upstream product

• 1111637-98-9 5-bromo-2,3-dimethyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 77992-44-0 5-bromo-2-hydrazinylpyridine 
• 78-93-3 butanone 
• 504-29-0 2-aminopyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 624-28-2 2,5-dibromopyridine 

Downstream Products

• 1111637-99-0 2,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

Preparation of 2,3-Disubstituted 5-Bromo-1 H -pyrrolo[2,3- b ]pyridine Framework by Fischer Cyclization

A simple synthesis of some hard-to-reach heterocycles containing 2,3-disubstituted 5-bromo-1H-pyrrolo[2,3-b]pyridine framework by FisNher indole cyclization in polyphosphoric acid has been developed. A particularly valuable feature of this synthetic route is the possibility to build a 5-bromo-7-azaindole scaffold with alkyl or aryl substituents at positions 2 and 3 from available starting materials.

IMIDAZOPYRIDIN-2-ONE DERIVATIVES

A compound represented by formula (I) having mTOR inhibitory activity or a pharmacologically acceptable salt thereof.

PYRAZOLE COMPOUNDS

The present invention is directed to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.