146667-87-0

Basic information

• Product Name: 3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester;1-Boc-3-Vinyl-piperidine;tert-Butyl 3-vinylpiperidine-1-carboxylate;tert-butyl 3-ethenylpiperidine-1-carboxylate
• CAS NO: 146667-87-0
• Molecular Formula: C12H21NO2
• Molecular Weight: 211.3
• Mol File: 146667-87-0.mol

Chemical Properties

• Boiling Point: 268.886°C at 760 mmHg
• Flash Point: 116.418°C
• Appearance: /
• Density: 1.028g/cm³
• Vapor Pressure: 0.007mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: 2-8°C
• PKA: -1.69±0.40(Predicted)
• CAS DataBase Reference: 3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester(146667-87-0)
• EPA Substance Registry System: 3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester(146667-87-0)

Safety Data

• Hazardous Substances Data: 146667-87-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester is used as a versatile building block for the synthesis of complex organic molecules, leveraging its distinct structural features and functional groups.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester is used as a key intermediate in the production of various drugs, owing to its potential to form diverse molecular structures that can target specific biological pathways.
Used in Agrochemical Industry:
3-Vinyl-piperidine-1-carboxylic acid tert-butyl ester is utilized as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides, due to its ability to create molecules with specific modes of action against pests and weeds.

InChI:InChI=1/C12H21NO2/c1-5-10-7-6-8-13(9-10)11(14)15-12(2,3)4/h5,10H,1,6-9H2,2-4H3

Upstream product

• 6293-56-7 3-pyridinylethanol 
• 39931-77-6 pyridin-3-yl-acetic acid ethyl ester 
• 146667-82-5 3-(2-ethyl)piperidine 
• 146667-81-4 3-(2-ethyl)pyridine 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 118156-93-7 3-formylpiperidine-1-carboxylic acid tert-butyl ester 
• 146667-85-8 tert-butyl 3-(2-<4-tolylsulfonyloxy>ethyl)-1-piperidinecarboxylate 
• 146667-83-6 tert-butyl 3-(2-ethyl)-1-piperidinecarboxylate 
• 146667-84-7 tert-butyl 3-(2-hydroxyethyl)-1-piperidinecarboxylate 

Relevant articles and documents

PYRIDO[3,4-B]PYRAZINE DERIVATIVES AS SYK INHIBITORS

A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, and autoimmune conditions.

PYRIDO[3,4-B]PYRAZINE DERIVATIVES AS SYK INHIBITORS

A compound of formula (I) or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, and autoimmune conditions.

Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators

Compounds of Formula I: wherein A, B, D, L, R1, R2, R3, R4, m, and n are as defined for Formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.

Synthesis of 3-Vinylpiperidine

A novel synthesis of 3-vinylpiperidine from commercially available ethyl 3-pyridylacetate is described.