118156-93-7

Basic information

• Product Name: 1-BOC-3-PIPERIDINECARBOXALDEHYDE
• Synonyms: N-BOC-3-PIPERIDINYLCARBOXALDEHYDE;N-BOC-3-FORMYLPIPERIDINE;BOC-3-PIPERIDINECARBOXALDEHYDE;BUTTPARK 147\06-01;1-BOC-3-PIPERIDINECARBOXALDEHYDE;1-N-BOC-3-FORMYLPIPERIDINE;3-FORMYLPIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Boc-3-formylpiperidine
• CAS NO: 118156-93-7
• Molecular Formula: C₁₁H₁₉NO₃
• Molecular Weight: 213.27
• Product Categories: pharmacetical;Piperidine
• Mol File: 118156-93-7.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 295.4 °C at 760 mmHg
• Flash Point: 132.5 °C
• Appearance: /
• Density: 1.114 g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -2.29±0.40(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: 1-BOC-3-PIPERIDINECARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-3-PIPERIDINECARBOXALDEHYDE(118156-93-7)
• EPA Substance Registry System: 1-BOC-3-PIPERIDINECARBOXALDEHYDE(118156-93-7)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 36/37/38-50-36-22
• Safety Statements: 26-36/37/39-61-37
• RIDADR: UN3077
• Hazardous Substances Data: 118156-93-7(Hazardous Substances Data)

Usage

Description

1-BOC-3-PIPERIDINECARBOXALDEHYDE, also known as N-Boc-3-piperidinecarboxaldehyde, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals and chemicals. It is characterized by its colorless liquid appearance and plays a significant role in the development of new compounds with potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
1-BOC-3-PIPERIDINECARBOXALDEHYDE is used as an organic chemical synthesis intermediate for the development of new pharmaceutical compounds. Its unique structure allows for the creation of a wide range of drugs with potential therapeutic applications, including those targeting central nervous system disorders, pain management, and other medical conditions.
Used in Chemical Industry:
1-BOC-3-PIPERIDINECARBOXALDEHYDE is also utilized as a key intermediate in the synthesis of various chemicals, such as agrochemicals, dyes, and other specialty chemicals. Its versatility in chemical reactions enables the production of a diverse array of products with specific properties and applications in different sectors.

InChI:InChI=1/C11H19NO3/c1-11(2,3)15-10(14)12-6-4-5-9(7-12)8-13/h8-9H,4-7H2,1-3H3

Upstream product

• 4606-65-9 3-(hydroxymethy)piperidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 114615-82-6 tetrapropylammonium perruthennate 
• 7529-22-8 4-methylmorpholine N-oxide 
• 116574-71-1 (±)-tert-butyl 3-(hydroxymethyl)piperidine-1-carboxylate 
• 79-37-8 oxalyl dichloride 
• 498-95-3 nipecotic acid 
• 71381-75-4 N-(tert-butyloxycarbonyl)nipecotic acid 
• 189442-78-2 (±)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 

Downstream Products

• 406212-53-1 tert-butyl 3-{2-amino-6-[2-(benzyloxy)phenyl]-3-cyano-4-pyridinyl}-1-piperidinecarboxylate 
• 406212-57-5 tert-butyl 3-{2-amino-6-[2,6-bis(benzyloxy)phenyl]-3-cyano-4-pyridinyl}-1-piperidinecarboxylate 
• 744216-05-5 2'-amino-6'-(2-benzyloxy-phenyl)-1,2,3,4,5,6-hexahydro-[3,4']bipyridinyl-3'-carbonitrile 
• 744216-06-6 2'-amino-6'-(2-benzyloxy-phenyl)-1-methyl-1,2,3,4,5,6-hexahydro-[3,4']bipyridinyl-3'-carbonitrile 
• 406212-54-2 tert-butyl 3-[2-amino-3-cyano-6-(2-hydroxyphenyl)-4-pyridinyl]-1-piperidinecarboxylate 
• 744216-09-9 3'-cyano-6'-(2-hydroxy-phenyl)-2'-methylamino-3,4,5,6-tetrahydro-2H-[3,4']bipyridinyl-1-carboxylic acid tert-butyl ester 
• 406212-70-2 2'-acetylamino-3'-cyano-6'-(2-hydroxy-phenyl)-3,4,5,6-tetrahydro-2H-[3,4']bipyridinyl-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

(E) and (Z)-3-styrylpiperidines as sigma ligands

A class of (E) and Q-3-styrylpiperidine derivatives was prepared as racemates and evaluated for affinity at σ binding sites labeled with [3H]-(±-SKF-10,047. Some of these compounds exhibited high affinity and selectivity for σ verus D1 and D2 binding sites.

NOVEL HISTONE METHYLTRANSFERASE INHIBITORS

The present invention relates to novel compounds of formula (I) as defined herein. The compounds are inhibitors of histone methyltransferases of the seven-beta-strand family, in particular of KMT9.

A kind of protease inhibitor and its preparation and use

The invention discloses a kind of protease inhibitors, and preparation method and application thereof. The invention discloses a kind of compounds and pharmaceutical compositions thereof, and a preparation method and application thereof. The invention relates to a kind of compounds capable of reducing or inhibiting activity of dual leucine zipper kinase in cells or a subject, and application of the compounds, or solvates, hydrates or medicinal salts thereof to prevent or treat patient diseases or related diseases caused by abnormity of dual leucine zipper kinase.