146880-01-5Relevant articles and documents
P-chiral phosphinoselenoic chlorides and phosphinochalcogenoselenoic acid esters: Synthesis, characterisation, and conformational studies
Kimura, Tsutomu,Murai, Toshiaki
, p. 952 - 959 (2007/10/03)
(Chemical Equation Presented) P-Chiral alkyl or aryl phenylphosphinoselenoic chlorides were obtained by reacting PhPCl2 with Grignard reagents and elemental selenium. P-Chiral dialkyl chlorides were also obtained by treating PCl3 with two different Grignard reagents and elemental selenium. The structure of the chloride was determined by X-ray molecular structure analysis. P-Chiral phosphinochalcogenoselenoic acid esters bearing a P=Se double bond were synthesized by treating the chlorides with alkali metal alkoxide and chalcogenolates, whereas those bearing a P-Se single bond were obtained by sequential treatment of the chlorides with sodium hydroxide, sulfide or selenide, and alkyl iodides. X-ray molecular structure analyses of esters showed that they adopted gauche conformations. The computational results supported the observed conformational preference. Natural bond orbital analyses of the model compounds showed that two types of nonbonding orbital interactions, nE′ → σ*P=E and nE → σ*P-E′, are important in these compounds. Linear correlations were observed between the experimental 77Se NMR chemical shifts or the coupling constants of P-Se bonds in the esters and the calculated P-Se bond lengths of the model compounds.
Asymmetric phosphinoselenoic chloride and method for producing the same
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Page 7, (2010/02/08)
An asymmetric phosphinoselenoic chloride of the present invention is represented by the general formula: wherein Ar represents an aryl group and R represents an aryl group, an alkyl group having 3 or more carbon atoms, or an alkoxy group. The asymmetric phosphinoselenoic chloride is a novel compound and is useful as synthetic raw materials, agricultural chemicals, pharmaceutical products and the like.
P-chiral phosphinoselenoic chlorides and optically active P-chiral phosphinoselenoic amides: Synthesis and stereospecific interconversion with extrusion and addition reactions of the selenium atom
Kimura, Tsutomu,Murai, Toshiaki
, p. 878 - 879 (2007/10/03)
An efficient synthesis of P-chiral phosphinoselenoic chlorides and the first optically active P-chiral phosphinoselenoic amides was successfully achieved. Stereospecific interconversion with the extrusion of selenium atom from optically active phosphinose
