147169-19-5

Basic information

• Product Name: BENZYL N-(CYCLOHEXYL[(4-METHYLPHENYL)SULFONYL]METHYL)CARBAMATE
• Synonyms: BENZYL N-(CYCLOHEXYL[(4-METHYLPHENYL)SULFONYL]METHYL)CARBAMATE;benzyl N-[cyclohexyl(4-methylbenzenesulfonyl)methyl]carbamate
• CAS NO: 147169-19-5
• Molecular Formula: C₂₂H₂₇NO₄S
• Molecular Weight: 401.52
• Mol File: 147169-19-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZYL N-(CYCLOHEXYL[(4-METHYLPHENYL)SULFONYL]METHYL)CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL N-(CYCLOHEXYL[(4-METHYLPHENYL)SULFONYL]METHYL)CARBAMATE(147169-19-5)
• EPA Substance Registry System: BENZYL N-(CYCLOHEXYL[(4-METHYLPHENYL)SULFONYL]METHYL)CARBAMATE(147169-19-5)

Safety Data

• Hazardous Substances Data: 147169-19-5(Hazardous Substances Data)

Upstream product

• 621-84-1 O-benzyl carbamate 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 646480-73-1 N-Benzyloxycarbonyl-1-cyclohexylbut-3-enylamine 
• 1217897-43-2 C₁₆H₂₀N₂O₂ 
• 1379681-83-0 N-benzyloxycarbonyl-1-cyclohexyl-3-phenylprop-2-yn-1-amine 
• 1243036-08-9 C₂₂H₃₁NO₆ 
• 1190880-23-9 C₂₃H₃₀O₅S 
• 1078719-41-1 (R)-benzyl N-[cyclohexyl(dimethoxyphosphoryl)methyl]carbamate 
• 271600-19-2 [(R)-1-Cyclohexyl-3-oxo-3-((1R,2R,4R)-1,7,7-trimethyl-2-trimethylsilanyloxy-bicyclo[2.2.1]hept-2-yl)-propyl]-carbamic acid benzyl ester 

Relevant articles and documents

Leaving group and regioselectivity switches in the aminoalkylation reaction of indoles and related heterocycles with α-amido sulfones

The regioselective aminoalkylation of indoles and related heterocycles with α-amido sulfones under basic conditions has been studied. The reaction that employed the MeMgBr/MgBr2 system provided high yields of 3-(1-carbamoylalkyl)indoles. On the other hand, the reaction that used Cs 2CO3 afforded 1-(1-carbamoylalkyl)indoles exclusively in high yields. The first reaction constitutes a switch of the leaving group of the α-amido sulfone in comparison to previously reported reactions between indoles and α-amido sulfones, which provided 3-(1-arylsulfonylalkyl) indoles. The second reaction constitutes a switch in the regioselectivity. The extensions of these C- and N-aminoalkylations starting from pyrroles and 7-azaindole have also been studied. Structurally diverse aminoalkylated indoles, pyrroles, and 7-azaindoles were obtained with excellent yield in most of the cases. The regioselective aminoalkylation of indoles and heterocycles with α-amido sulfones under basic conditions is described. The reaction with MeMgBr/MgBr2 gives 3-(1-carbamoylalkyl)indoles, whereas employing Cs2CO3 yields 1-(1-carbamoylalkyl)indoles. The first case presents a switch of the leaving group of the α-amido sulfone, whereas the second demonstrates a switch in the regioselectivity. Copyright

Regioselective arylations of α-amido sulfones with electron-rich arenes through friedel-crafts alkylations catalyzed by ferric chloride hexahydrate: Synthesis of unsymmetrical and bis-symmetrical triarylmethanes

Ferric chloride hexahydrate is a highly efficient catalyst for the regioselective arylation of α-amido sulfones. The products undergo further Friedel-Crafts alkylations with heteroaromatic or electron-rich arenes to afford unsymmetrical or bis-symmetrical

A mild and efficient catalytic mannich-type reaction as a simple access to N -benzyloxycarbonyl -amino ketones

N-Benzyloxycarbonylamino sulfones react with aromatic ketones in the presence of catalytic amount of boron trifluoride-diethyl ether at room temperature to afford the corresponding protected β-amino ketones in high yields (71-87%). Georg Thieme Verlag Stu

Indium triflate-catalyzed allylation reactions of N-sulfonyl aldimines or N-alkoxycarbonylamino p-tolylsulfones with allyltrimethylsilane: Synthesis of protected homoallylic amines

Indium triflate-catalyzed allylation reactions of N-sulfonyl aldimines or N-alkoxyloxycarbonylamino p-tolylsulfone with allyltrimethylsilane have been successfully developed to produce protected homoallylic amines.

InBr3: A versatile catalyst for the different types of Friedel-Crafts reactions

(Chemical Equation Presented) Mild and efficient InBr3-catalyzed Friedel-Crafts alkylation of heteroaromatic or electron-rich aromatic compounds with α-amido sulfones at room temperature in CH2Cl2 has been developed. The p

Configurational stability of chiral, nonconjugated nitrogen-substituted organolithium compounds generated by tin-lithium exchange of N-[(1-Tri-n-butylstannyl)alkyl]imidazolidin-2-ones and -oxazolidin-2-ones

Chiral, nonracemic, nonconjugated, acyclic nitrogen-substituted organolithium compounds were generated in order to study the configurational stability of such species. The organolithium compounds were generated by tin-lithium exchange on N-[(1-tri-n-butyl