147723-92-0 Usage
Uses
Used in Pharmaceutical Research:
(2E)-3-[4-(AMINOSULFONYL)PHENYL]ACRYLIC ACID is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique chemical structure and reactivity.
Used in Organic Synthesis:
(2E)-3-[4-(AMINOSULFONYL)PHENYL]ACRYLIC ACID is used as a building block for the creation of a wide range of organic compounds, contributing to the development of new materials and chemical products.
Used in Medicinal Applications:
(2E)-3-[4-(AMINOSULFONYL)PHENYL]ACRYLIC ACID is used as a potential treatment for inflammatory conditions such as rheumatoid arthritis, leveraging its anti-inflammatory properties.
Used in Antioxidant Therapies:
(2E)-3-[4-(AMINOSULFONYL)PHENYL]ACRYLIC ACID is used as an antioxidant agent to combat oxidative stress and related conditions, potentially offering therapeutic benefits.
Used in Cancer Treatment Research:
(2E)-3-[4-(AMINOSULFONYL)PHENYL]ACRYLIC ACID is used in the investigation of novel cancer treatments, exploring its potential to target and treat cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 147723-92-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,7,2 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 147723-92:
(8*1)+(7*4)+(6*7)+(5*7)+(4*2)+(3*3)+(2*9)+(1*2)=150
150 % 10 = 0
So 147723-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO4S/c10-15(13,14)8-4-1-7(2-5-8)3-6-9(11)12/h1-6H,(H,11,12)(H2,10,13,14)/b6-3+
147723-92-0Relevant articles and documents
Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors
Angeli, Andrea,Bozdag, Murat,Carta, Fabrizio,Gumus, Arzu,Peat, Thomas S.,Selleri, Silvia,Supuran, Claudiu T.
supporting information, (2021/08/16)
We report for the first time a small series of compounds endowed in vitro with inhibitory properties for the human (h) expressed Carbonic Anhydrase (CAs, E.C. 4.2.1.1) enzymes of physiological interest (i.e. I, II, VA, IX and XII) and bearing the pyrazolo[1,5-a]pyrimidine (PP) scaffold at the tail section. Among the series reported, 1a-3a, 7a, 8a, 1b and 2b resulted effective ligands and with good selectivities for the hCAs II, IX or XII. In consideration of the nearly matching KI values of 7a for both the hCA II and IX (i.e. 26.4 and 23.0 nM respectively) we explored its binding mode within the CA IX mimic isoform by means of X-ray crystal experiments on the corresponding adduct.
Piperidine derivative and pharmaceutical composition containing it
-
, (2008/06/13)
Piperidine derivatives of formula (I) and their pharmaceutically acceptable salts have antihypertensive action. The compounds may be included in pharmaceutical compositions for oral or parenteral administration.
