147739-88-6

Basic information

• Product Name: 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine
• Synonyms: 6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRIDINE;5H-Pyrrolo[3,4-b]pyridine,6,7-dihydro-(9CI);6,7-Dihydro-5H-pyrrolo[3,4,6]pyridine;6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRIDINE HCL 97+%;6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine 2HCl;5H-Pyrrolo[3,4-b]pyridine, 6,7-dihydro-;4-b]pyridine hydrochloride;6,7-Dihydro-5H-pyrrolo[3,4-b]pyridineHCl
• CAS NO: 147739-88-6
• Molecular Formula: C₇H₈N₂
• Molecular Weight: 120.15
• Product Categories: PYRIDINE;PYRROLIDINE;Amines and Anilines;Heterocycles;pharmacetical;CHIRAL CHEMICALS;Heterocycle-Pyridine series
• Mol File: 147739-88-6.mol

Chemical Properties

• Boiling Point: 215.839 °C at 760 mmHg
• Flash Point: 84.337 °C
• Appearance: /
• Density: 1.115 g/cm³
• Vapor Pressure: 0.00173mmHg at 25°C
• PKA: 6.68±0.20(Predicted)
• CAS DataBase Reference: 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine(147739-88-6)
• EPA Substance Registry System: 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine(147739-88-6)

Safety Data

• Hazardous Substances Data: 147739-88-6(Hazardous Substances Data)

Usage

Uses

6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine DiHCl

InChI:InChI=1/C7H8N2.2ClH/c1-2-6-4-8-5-7(6)9-3-1;;/h1-3,8H,4-5H2;2*1H

Upstream product

• 45754-12-9 2,3-bis(chloromethyl)-pyridine 
• 423169-40-8 2,3-bis(hydroxymethyl)pyridine hydrochloride 
• 605-38-9 dimethyl 2,3-pyridinedicarboxylate 
• 89-00-9 Pyridine-2,3-dicarboxylic acid 
• 109966-30-5 6-benzyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine 

Downstream Products

• 915104-66-4 N-(4-Chlorophenyl)-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carbothioamide 
• 1616709-24-0 2-((5H-pyrrolo[3,4-b]pyridine-6(7H)-yl)methyl)-N-(2,4-dimethoxybenzyl)-7-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-amine 
• 1460032-22-7 4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde 
• 1460032-19-2 2,5-dioxopyrrolidin-1-yl 4-[(4-chloro-2-{5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}phenyl)methyl]piperazine-1-carboxylate 
• 1460032-30-7 1-[(4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]phenyl)methyl]piperazine 
• 1460032-27-2 tert-butyl 4-[(4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]phenyl)methyl]piperazine-1-carboxylate 
• 1362159-82-7 C₂₁H₁₉N₃O₃S 
• 1438073-50-7 N-(3-chloro-4-fluorophenyl)-6-(3-(6-ethyloctahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)propoxy)-7-methoxyquinazolin-4-amine 
• 1438073-38-1 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(6-methyloctahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)propoxy)quinazolin-4-amine 
• 1438073-32-5 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)propoxy)quinazolin-4-amine 
• 1438082-78-0 tert-butyl 1-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)hexahydro-1H-pyrrolo[3,4-b] pyridine-6(2H)-carboxylate 
• 186203-81-6 tert-butyl hexahydro-1H-pyrrolo[3.4-b]pyridine-6(2H)-carboxylate 
• 1424330-26-6 C₁₉H₁₆Cl₂N₄O₂ 
• 1059172-92-7 tert-butyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate 

Relevant articles and documents

A robust process for an mGluR5 negative allosteric modulator: Difluoromethylation and sonogashira coupling on large scale

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Compounds of formula (I), or a pharmaceutically acceptable salt, solvate, ester or amide thereof, wherein R1 represents [CH2]n-R2; R2 represents H, C1-6 alkyloxy or Het; n represents a numb