Synthesis of 2--1-indanones by Anionic Cyclization of Phenylalanine-Derived Oxazolidinones
A novel preparation of N-(phenylfluorenyl)-2-amino-1-indanones is described.The key step is the cyclization of aryl-substituted o-bromophenylalanine-derived oxazolidinones with n-BuLi by halogen-metal exchange followed by in situ intramolecular acylation