Synthesis of 2--1-indanones by Anionic Cyclization of Phenylalanine-Derived Oxazolidinones

DOI: 10.1021/jo00062a018

Source and publish data:

Journal of Organic Chemistry p. 2763 - 2767 (1993)

Update date:2022-07-31

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Authors:

Paleo, M. Rita

Castedo, Luis

Dominguez, Domingo

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Article abstract of DOI:10.1021/jo00062a018

A novel preparation of N-(phenylfluorenyl)-2-amino-1-indanones is described.The key step is the cyclization of aryl-substituted o-bromophenylalanine-derived oxazolidinones with n-BuLi by halogen-metal exchange followed by in situ intramolecular acylation

Full text of DOI:10.1021/jo00062a018

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