148028-26-6Relevant articles and documents
One Pot Synthesis of N-Derivatized 2-Oxazolidinones from Amino Alcohol Carbamates
Huwe, Christoph M.,Blechert, Siegfried
, p. 9533 - 9536 (1994)
A one pot protocol for the synthesis of N-derivatized 2-oxazolidinones from amino alcohol carbamates is described.The method is exceptionally useful if the parent amino acids are prepared in their enantiopure forms via enzymatic resolution of the racemic carbamate esters.
Conjugate addition of organocuprates to methyl crotonate linked to chiral oxazolidones
Le Coz,Mann
, p. 165 - 171 (2007/10/02)
Conjugate addition of various sp3 dialkylcuprates were performed on enoates 4a-b, γ-aminocrotonate equivalents embodied in chiral oxazolidones. The diastereoselectivity is good to moderate and allows the access to homochiral β-substituted GABA analogues.