148185-66-4

Basic information

• Product Name: 4,7-dibromo-1H-benzo[d]imidazole
• Synonyms: 4,7-dibromo-1H-benzo[d]imidazole
• CAS NO: 148185-66-4
• Molecular Formula: C₇H₄Br₂N₂
• Molecular Weight: 275.92806
• Mol File: 148185-66-4.mol

Chemical Properties

• Melting Point: 264-266 °C(Solv: dichloromethane (75-09-2); water (7732-18-5))
• Boiling Point: 462.4±25.0 °C(Predicted)
• Appearance: /
• Density: 2.164±0.06 g/cm3(Predicted)
• PKA: 8.65±0.30(Predicted)
• CAS DataBase Reference: 4,7-dibromo-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-dibromo-1H-benzo[d]imidazole(148185-66-4)
• EPA Substance Registry System: 4,7-dibromo-1H-benzo[d]imidazole(148185-66-4)

Safety Data

• Hazardous Substances Data: 148185-66-4(Hazardous Substances Data)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 15155-41-6 4,7-dibromobenzo[c][1,2,5]thiadiazole 
• 122-51-0 orthoformic acid triethyl ester 
• 64-18-6 formic acid 
• 69272-50-0 1,2-diamine-3,6-dibromobenzene 
• 149-73-5 trimethyl orthoformate 
• 273-13-2 benzo[1,2,5]thiadiazole 

Downstream Products

• 1417568-64-9 4,7-bis((4-methoxyphenyl)thio)-1H-benzo[d]imidazole 
• 1467575-61-6 1-benzyl-4,7-dibromo-1H-benzimidazole 
• 1998160-90-9 4,4'-(1H-benzo[d]imidazole-4,7-diyl)dianiline 
• 2092907-94-1 4,7-bis(4-formylbenzyl)-1-methyl-1H-benzimidazole 
• 1417568-60-5 4,7-bis((4-methoxyphenyl)sulfonyl)-1H-benzo[d]imidazole 

Relevant articles and documents

UiO-68-PT MOF-Based Sensor and Its Mixed Matrix Membrane for Detection of HClO in Water

As an important type of reactive oxygen species (ROS), hypochloric acid (HClO) is closely linked with our daily life, and its convenient and rapid detection is very significant and imperative. Fluorescent and visual probes are being recognized as powerful and convenient tools for detection of ROS in the environment and living organisms by visualizing and imaging. In this contribution, a new metal-organic framework-based fluorescent probe UiO-68-PT, which was generated from a phenthiazine-decorated benzimidazole bridging dicarboxyl ligand and ZrCl4 under solvothermal conditions via in situ one-pot approach, is reported. The obtained UiO-68-PT features a unique HClO and Vitamin C-triggered reversible redox process, which is accompanied by both visual and fluorescence changes. Therefore, it can be a highly sensitive, specific, and reusable sensor to detect HClO species in water via both visual and fluorogenic observation (turn-on). Furthermore, its mixed membrane material (MMM) was fabricated by the combination of UiO-68-PT and poly(vinyl alcohol), and the obtained hydrophilic MMM can be used as a reversible colorimetric card for visual detection of the HClO in aqueous solution.

Ionic Covalent Organic Frameworks: Design of a Charged Interface Aligned on 1D Channel Walls and Its Unusual Electrostatic Functions

Covalent organic frameworks (COFs) have emerged as a tailor-made platform for designing layered two-dimensional polymers. However, most of them are obtained as neutral porous materials. Here, we report the construction of ionic crystalline porous COFs wit

Synthesis of new azole phosphonate precursors for fuel cells proton exchange membranes

Herein we present the synthesis and characterization of new phosphonate-, bisphosphonate- and hydroxybisphosphonatebenzimidazole derivatives substituted at the N-1 position and new regioisomers phosphonate-, bisphosphonate-, and hydroxybisphosphonatebenzo

Porous organic polymer with: In situ generated palladium nanoparticles as a phase-transfer catalyst for Sonogashira cross-coupling reaction in water

A new Pd nanoparticle loaded and imidazolium-ionic liquid decorated organic polymer of Pd@PTC-POP was readily fabricated via a Pd(PPh3)4 catalysed in situ one-pot Suzuki cross-coupling reaction between imidazolium attached dibromoben

Phenothiazine-based metal organic framework material as well as preparation method and application thereof

The invention provides a phenothiazine-based nano metal organic framework material which takes a formula (I) compound as an organic ligand, the structure of the formula (I) compound is as shown in thespecification, a NMOFs sensor with high reactivity detects HClO, and has high selectivity, and the detection accuracy is guaranteed. Compared with a common organic polymer-like HClO sensor, the NMOFssensor has the advantage of being visible by naked eyes.

Effect of the functionalisation route on a Zr-MOF with an Ir-NHC complex for catalysis

A new iridium N-heterocyclic carbene (NHC) metallolinker has been synthesised and introduced into a metal-organic framework (MOF), for the first time, via two different routes: direct synthesis and postsynthetic exchange (PSE). The two materials were compared in terms of the Ir loading and distribution using X-ray energy dispersive spectroscopy (EDS), the local Ir structure using X-ray absorption spectroscopy (XAS) and the catalytic activity. The materials showed good activity and recyclability as catalysts for the isomerisation of an allylic alcohol.

New azaheterocyclic aromatic diphosphonates for hybrid materials for fuel cell applications

New azaheterocyclic aromatic diphosphonate derivatives of benzimidazole and benzotriazole were synthesized by nickel-catalyzed Arbuzov reaction of 4,7-dibromo-2,1,3-benzothiadiazole with triethyl phosphite, followed by reductive sulfur extrusion reaction

SULFONE DERIVATIVES AND THEIR USE AS PKM2 MODULATORS FOR THE TREATMENT OF CANCER

Provided herein is novel compound of the general formula (I), its tautomeric forms, its stereoisomers, its analogs, its prodrugs, its isotopes, its N- oxides, its metabolites, its pharmaceutically acceptable salts, its polymorphs, its solvates, its optical isomers, its clathrates, its co-crystals, its combinations with suitable medicament and pharmaceutical compositions comprising the same. Also provided is method of treating a disease responsive to activation of human PKM2 by administration of said compound and its use as PKM2 modulator in various pathological conditions.

A metal-organic framework with covalently bound organometallic complexes

A procedure for making covalently linked organometallic complexes within the pores of metal-organic frameworks (MOFs) has been described. An N-heterocyclic carbene precursor containing link L0 was prepared and then constructed into a MOF-5-type structure (IRMOF-76). Attempts to produce covalently bound organometallic complexes in IRMOF-76 were unsuccessful. An alternative way of linking the first metalated link, L1, into the desired metalated MOF structure, IRMOF-77, was successful. IRMOF-76 and-77 were characterized by single-crystal X-ray studies. Demonstration of permanent porosity and successful substitution of the pyridine coligand in IRMOF-77 are also described.