- Enantioselective Reductive Coupling of Imines Templated by Chiral Diboron
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We herein report a general, practical, and highly efficient method for asymmetric synthesis of a wide range of chiral vicinal diamines via reductive coupling of imines templated by chiral diboron. The protocol features high enantioselectivity and stereospecificity, mild reaction conditions, simple operating procedures, use of readily available starting materials, and a broad substrate scope. The method signifies the generality of diboron-enabled [3,3]-sigmatropic rearrangement.
- Chen, Dongping,Li, Kaidi,Tang, Wenjun,Xu, Guangqing,Xu, Ronghua,Zhou, Mingkang
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supporting information
p. 10337 - 10342
(2020/07/04)
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- Asymmetric transfer hydrogenation of aromatic ketones catalyzed by new chiral C2-symmetric bis(sulfonyl) tetraaza ligands complexed with [Ru(η6-p-cymene)Cl2]2 in water
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In this report, a new series of C2-symmetric bis(sulfonyl) tetraaza ligands were synthesized from (1S,2S)-1,2-diarylethylenediamine analogues and tested in the asymmetric transfer hydrogenation (ATH) of aromatic ketones by complexing with [Ru(η6-p-cymene)Cl2]2 employing sodium formate as hydrogen source in neat water. A moderate to excellent conversion (~99.8 %) and overall satisfying enantioselectivity (~92.8 %) were obtained with varied electronic and steric effects of the substituents on ligands and substrates.
- Liu, Xungao,Zhang, Tian,Hu, Yingying,Shen, Liang
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p. 1289 - 1295
(2014/07/21)
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- Hydrogen bonding makes a difference in the rhodium-catalyzed enantioselective hydrogenation using monodentate phosphoramidites
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A new generation of monodentate phosphoramidite ligands bearing a primary amine moiety was found to display comparable or better efficiency than bisphosphines in the Rh-catalyzed asymmetric hydrogenation of challenging substrates, such as (Z)-methyl α-ace
- Liu, Yan,Sandoval, Christian A.,Yamaguchi, Yoshiki,Zhang, Xue,Wang, Zheng,Kato, Koichi,Ding, Kuiling
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p. 14212 - 14213
(2008/02/09)
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- New chiral 1,2-diamines and their use in zinc-catalyzed asymmetric hydrosilylation of acetophenone
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The preparation of two new series of chiral 1,2-diamines and their use in the [ZnR2-diamine]-catalyzed asymmetric hydrosilylation of acetophenone with poly(methylhydrosiloxane) (PMHS) in an aprotic medium is reported. The effect of structural m
- Bette, Virginie,Mortreux, Andre,Ferioli, Federico,Martelli, Gianluca,Savoia, Diego,Carpentier, Jean-Francois
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p. 3040 - 3045
(2007/10/03)
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- Synthesis and evaluation of the anti-mammary tumor activity and of the estrogenic side effects of platinum(II) complexes
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The synthesis and structural characterization of mammary tumor-inhibiting, diastereomeric platinum(II) complexes with 2,6-Cl2, 2F, 6-Cl, 2-Cl, 6-F and 2,6-F2 substituents (1-PtSO4 to 4-PtSO4) are describ
- Gust, R,Schoenenberger, H
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p. 103 - 115
(2007/10/02)
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