148541-80-4

Basic information

• Product Name: 1H-Pyrrole,3-fluoro-1-phenyl-(9CI)
• Synonyms: 1H-Pyrrole,3-fluoro-1-phenyl-(9CI)
• CAS NO: 148541-80-4
• Molecular Formula: C10H8FN
• Molecular Weight: 161.178
• Product Categories: HALIDE
• Mol File: 148541-80-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrole,3-fluoro-1-phenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole,3-fluoro-1-phenyl-(9CI)(148541-80-4)
• EPA Substance Registry System: 1H-Pyrrole,3-fluoro-1-phenyl-(9CI)(148541-80-4)

Safety Data

• Hazardous Substances Data: 148541-80-4(Hazardous Substances Data)

Upstream product

• 1252030-16-2 C₁₃H₁₉F₂NOSi 
• 586-96-9 Nitrosobenzene 
• 148541-87-1 5-fluoro-6-hydroxy-2-phenyl-3,6-dihydro-1,2-oxazine 

Relevant articles and documents

Efficient preparation of 3-fluoropyrrole derivatives

Noble N-substituted-3-fluoropyrroles derivatives were prepared from new precursor via ring formation. The addition reaction of ethyl iododifluoroacetate to vinyl trimethylsilane under the Cu(0) catalyst resulted in the formation of ethyl-2,2-difluoro-4-iodo-4-(trimethylsilyl)butanolate, which reacted with diisobutylaluminium hydride at- 30 °C to yield 2,2-diflouro-4-iodo-4- (trimethylsilyl)butanal. Finally, a series of N-substituted-3-fluoropyrrole derivatives were synthesized by the reaction of 2,2-diflouro-4-iodo-4- (trimethylsilyl)butanal with NH4OH or primary amines followed by reaction with KF solution.

A novel and versatile access to fluorinated carbo- and heterocyclic compounds employing electron-rich fluorodienes as cycloaddition components

The readily accessible 2-fluoro-1-trimethylsilyloxy-1,3-dienes undergo Diels-Alder type cycloaddition with a variety of dienophiles under mild conditions. In this way, fluoro-2-cyclohexenols, fluoro-2,5-dihydropyranols, fluoro-2,5-dihydro-2-pyridinols, fl