1252030-16-2

Basic information

• Product Name: C₁₃H₁₉F₂NOSi
• Synonyms: C₁₃H₁₉F₂NOSi
• CAS NO: 1252030-16-2
• Molecular Weight: 271.382
• Mol File: 1252030-16-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₉F₂NOSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₉F₂NOSi(1252030-16-2)
• EPA Substance Registry System: C₁₃H₁₉F₂NOSi(1252030-16-2)

Safety Data

• Hazardous Substances Data: 1252030-16-2(Hazardous Substances Data)

Upstream product

• 1252030-07-1 2,2-difluoro-4-iodo-4-(trimethylsilyl)butanal 
• 62-53-3 aniline 

Downstream Products

• 148541-80-4 1-phenyl-3-fluoropyrrole 

Relevant articles and documents

Efficient preparation of 3-fluoropyrrole derivatives

Noble N-substituted-3-fluoropyrroles derivatives were prepared from new precursor via ring formation. The addition reaction of ethyl iododifluoroacetate to vinyl trimethylsilane under the Cu(0) catalyst resulted in the formation of ethyl-2,2-difluoro-4-iodo-4-(trimethylsilyl)butanolate, which reacted with diisobutylaluminium hydride at- 30 °C to yield 2,2-diflouro-4-iodo-4- (trimethylsilyl)butanal. Finally, a series of N-substituted-3-fluoropyrrole derivatives were synthesized by the reaction of 2,2-diflouro-4-iodo-4- (trimethylsilyl)butanal with NH4OH or primary amines followed by reaction with KF solution.