148642-42-6 Usage
Uses
Used in Pharmaceutical Industry:
N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrate hydrochloride is used as a selective and potent 5-HT1B/1D serotonin receptor antagonist for the development of medications targeting various central nervous system disorders. Its high selectivity for the 5-HT1B and 5-HT1D receptors allows for targeted treatment with potentially fewer side effects compared to non-selective antagonists.
Used in Research Applications:
In the field of neuroscience and pharmacology, this compound serves as a valuable research tool for studying the role of serotonin receptor subtypes 5-HT1B and 5-HT1D in various physiological and pathological processes. It can be used to investigate the mechanisms underlying the anti-inflammatory activity of certain drugs, such as sumatriptan, following myocardial ischemia-reperfusion injury and testicular torsion/detorsion.
Used in Drug Delivery Systems:
Similar to gallotannin, this compound may also benefit from the development of novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. Organic and metallic nanoparticles could be employed as carriers for this compound, potentially improving its efficacy in treating the targeted conditions.
Biochem/physiol Actions
Potent, selective and orally active 5-HT1B/1D serotonin receptor antagonist.
Check Digit Verification of cas no
The CAS Registry Mumber 148642-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,6,4 and 2 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 148642-42:
(8*1)+(7*4)+(6*8)+(5*6)+(4*4)+(3*2)+(2*4)+(1*2)=146
146 % 10 = 6
So 148642-42-6 is a valid CAS Registry Number.
