148854-13-1

Basic information

• Product Name: Pyrimidine,5-(trimethylsilyl)-(9CI)
• Synonyms: Pyrimidine,5-(trimethylsilyl)-(9CI);5-(triMethylsilyl)pyriMidine;trimethyl(pyrimidin-5-yl)silane
• CAS NO: 148854-13-1
• Molecular Formula: C7H12N2Si
• Molecular Weight: 152.272
• Product Categories: SILYL
• Mol File: 148854-13-1.mol

Chemical Properties

• Boiling Point: 200.8±13.0 °C(Predicted)
• Appearance: /
• Density: 0.94±0.1 g/cm3(Predicted)
• PKA: 1.78±0.10(Predicted)
• CAS DataBase Reference: Pyrimidine,5-(trimethylsilyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine,5-(trimethylsilyl)-(9CI)(148854-13-1)
• EPA Substance Registry System: Pyrimidine,5-(trimethylsilyl)-(9CI)(148854-13-1)

Safety Data

• Hazardous Substances Data: 148854-13-1(Hazardous Substances Data)

Upstream product

• 4595-59-9 5-bromopyrimidine 
• 75-77-4 chloro-trimethyl-silane 

Relevant articles and documents

Using signal amplification by reversible exchange (SABRE) to hyperpolarise 119Sn and 29Si NMR nuclei

The hyperpolarisation of the 119Sn and 29Si nuclei in 5-(tributylstannyl)pyrimidine (ASn) and 5-(trimethylsilyl)pyrimidine (BSi) is achieved through their reaction with [IrCl(COD)(IMes)] (1a) or [IrCl(COD)(SIMes)] (1b) and parahydrogen via the SABRE process. 1a exhibits superior activity in both cases. The two inequivalent pyrimidine proton environments of ASn readily yielded signal enhancements totalling ～2300-fold in its 1H NMR spectrum at a field strength of 9.4 T, with the corresponding 119Sn signal being 700 times stronger than normal. In contrast, BSi produced analogous 1H signal gains of ～2400-fold and a 29Si signal that could be detected with a signal to noise ratio of 200 in a single scan. These sensitivity improvements allow NMR detection within seconds using micromole amounts of substrate and illustrate the analytical potential of this approach for high-sensitivity screening. Furthermore, after extended reaction times, a series of novel iridium trimers of general form [Ir(H)2Cl(NHC)(μ-pyrimidine-κN:κN′)]3 precipitate from these solutions whose identity was confirmed crystallographically for BSi.

Silyl heterocyclic fungicides

Fungicidal heterocyclic silyl compounds of the general formula STR1 have been discovered wherein Het is a six membered heterocyclic moiety; R is hydrogen or a trisubstituted silyl group; R1, R2 and R3 are independently selected from substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or pyridyl groups; m is 0 or 1 and n is zero, one or two.