149210-18-4

Basic information

• Product Name: 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID
• Synonyms: 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID
• CAS NO: 149210-18-4
• Molecular Formula: C11H8N2O2S
• Molecular Weight: 232.26
• Mol File: 149210-18-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID(149210-18-4)
• EPA Substance Registry System: 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID(149210-18-4)

Safety Data

• Hazardous Substances Data: 149210-18-4(Hazardous Substances Data)

Upstream product

• 1477-42-5 4-methyl-1,3-benzothiazol-2-amine 
• 149210-23-1 ethyl 12-methyl-7-thia-2,5-diazatricyclo[6.4.0.0^2,6]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylate 

Relevant articles and documents

IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS

A compound of formula (I) or a pharmaceutically acceptable salt thereof. The compound is useful for use in the treatment of cancer, an inflammatory disorder,an autoimmunity disorder or a neurodegenerative disorder.

Synthesis and pharmacological activity of imidazo[2,1-b]benzothiazole acids

We have prepared twelve imidazo[2,1-b]benzothiazole carboxylic and acetic acids by reaction of substituted 2-aminobenzothiazoles with ethyl brompyruvate and 4-chloroacetoacetate, respectively. The acids, obtained from esters by hydrolysis, were tested for their antiinflammatory, analgesic and ulcerogenic activities.