149625-48-9Relevant articles and documents
Synthesis of 2-acetamido-1,2,4-trideoxy-1,4-imino-D-galactitol and -D-glucitol for evaluation as glycosidase inhibitors
Croucher, Paul D.,Furneaux, Richard H.,Lynch, Gregory P.
, p. 13299 - 13312 (2007/10/02)
The title compounds, galacto-1 and gluco-2, were synthesised from N-acetyl-D-glucosamine via a common 1,4-diol intermediate that underwent transformations involving either a single or double inversion of stereochemistry at C-4, respectively. In the double
Synthesis of 2-acetamido-1,2,4-trideoxy-1,4-imino-D-galactitol, a new hexosaminidase inhibitor
Furneaux,Lynch,Way,Winchester
, p. 3477 - 3480 (2007/10/02)
2-Acetamido-1,2,4-trideoxy-1,4-imino-D-galactitol was synthesised from 2-acetamido-2-deoxy-D-glucose in 12 steps and was shown to be a modest hexosaminidase inhibitor.