149632-73-5

Usage

Uses

Used in Organic Synthesis:
Tert-butyl carbamate is used as a reagent in organic synthesis for various chemical reactions. Its ability to act as a protecting group for amines makes it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, tert-butyl carbamate is utilized in the production of various drugs. Its versatility as a reagent and protecting group contributes to the development of new and innovative pharmaceutical compounds.
Used in Agrochemical Manufacturing:
Tert-butyl carbamate is also employed in the manufacturing of agrochemicals, such as pesticides and herbicides. Its use in these applications helps to improve the efficiency and effectiveness of these products.
Used in Polymer Production:
In the polymer industry, tert-butyl carbamate is used in the manufacturing process of various types of polymers. Its properties make it suitable for use in the production of polymers with specific characteristics and applications.

Upstream product

• 78981-25-6 tert-butyl (1-amino-1-oxopropan-2-yl)carbamate 
• 3744-87-4 N-t-butyloxycarbonyl-DL-alanine 
• 147252-84-4 tert-butyl (1-hydroxypropan-2-yl)carbamate 
• 6627-89-0 tert-butyl phenyl carbonate 
• 78-90-0 1,2-diaminopropan 
• 129319-71-7 (+/-)-N-(tert-Butoxycarbonyl)-2-methylaziridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 149602-64-2 1-azido-2-(N-tert-butoxycarbonylamino)propane 

Downstream Products

• 769969-61-1 (2R,5S)-1-benzyl-5-(2-tert-butoxycarbonylamino-propylcarbamoyl)pyrrolidine-2-carboxylic acid ethyl ester 
• 1056117-87-3 [2-(2-Amino-phenylamino)-1-methyl-ethyl]-carbamic acid tert-butyl ester 
• 170116-52-6 N-(2'-tert-butylcarbamatopropyl)-2-nitroaniline 

Relevant academic research and scientific papers

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents

A series of novel carbazole-containing amides and ureas were synthesized. A structure–activity relationship study of these compounds led to the identification of potent cryptochrome modulators. Based on the desired pharmacokinetic/pharmacodynamic parameters and the results of efficacy studies in db/db mice, compound 50 was selected for further profiling.

CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS

The subject matter herein is directed to carbazole-containing amide, carbamate, and urea derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, D, E, G, J, L, M, Q, a, and b are accordingly described. Also provided are pharmaceutical compositions containing the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, complications associated with diabetes, Cushing's syndrome, NASH, NAFLD, asthma, and COPD.

MACROCYCLIC RIP2 KINASE INHIBITORS

The present invention relates to macrocyclic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of RIP2 and/or mutants thereof, for use in the diagnosis, prevention and/or treatment of RIP2-kinase associated diseases. Moreover, the present invention provides methods of using said compounds, for instance as a medicine or diagnostic agent.

PIPERAZINYL ANTIVIRAL AGENTS

Provided are compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).

Compounds specific to adenosine A1 receptors and uses thereof

This invention pertains to compounds which specifically inhibit the adenosine A1 receptor and the use of these compounds to treat a disease associated with A1 adenosine receptors in a subject.

Synthesis of Novel 1-, 1,4- and 1,7-Substituted 2-Mercapto- and 2-Methylmercapto- Benzimidazoles: Acyclic Analogues of the HIV-1 RT Inhibitor, TIBO

Synthetic approaches towards acyclic analogues of the HIV-1 RT inhibitor TIBO ring system, lacking either the diazepine C7 methylene, C5-N6 bond or the N1-N6 two-carbon bridge, are reported, utilizing ring opening reactions of 2-methylaziridines.A number of isomeric 2-methylmercaptobenzimidazole analogues have also been prepared, and the regiochemistry of 2-methylmercaptobenzimidazole alkylations is discussed, as a convenient route to 1,2,7-trifunctionalized benzimidazoles.