78-90-0

Basic information

• Product Name: 1,2-Diaminopropane
• Synonyms: 1,2-PROPYLENEDIAMINE;1,2-PROPANEDIAMINE;1,2-DIAMINOPROPANE;12AP;PROPYLENE-1,2-DIAMINE;PROPYLENEDIAMINE;1,2-Proplenediamine;2,3-diaminopropane
• CAS NO: 78-90-0
• Molecular Formula: C₃H₁₀N₂
• Molecular Weight: 74.12
• EINECS: 201-155-9
• Product Categories: Intermediates of Dyes and Pigments;straight chain compounds;Aliphatics;Amines;Isotope Labeled Compounds;Isotope Labelled Compounds;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Polyamines
• Mol File: 78-90-0.mol
• Article Data: 23

Chemical Properties

• Melting Point: -37 °C
• Boiling Point: 120-122 °C(lit.)
• Flash Point: 92 °F
• Appearance: /
• Density: 0.87 g/mL at 25 °C(lit.)
• Vapor Density: 2.6 (vs air)
• Vapor Pressure: 14 mm Hg ( 20 °C)
• Refractive Index: n20/D 1.446
• Storage Temp.: Flammables area
• Solubility: H2O: very soluble
• PKA: 9.82(at 25℃)
• Explosive Limit: 2.2-11.1%(V)
• Water Solubility: SOLUBLE
• Sensitive: Air Sensitive & Hygroscopic
• Stability: Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
• Merck: 14,7852
• BRN: 605274
• CAS DataBase Reference: 1,2-Diaminopropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Diaminopropane(78-90-0)
• EPA Substance Registry System: 1,2-Diaminopropane(78-90-0)

Safety Data

• Hazard Codes: C
• Statements: 10-21/22-35-42/43
• Safety Statements: 26-37/39-45-36/37/39-23
• RIDADR: UN 2258 8/PG 2
• WGK Germany: 1
• RTECS: TX6650000
• F: 3-10-23
• TSCA: Yes
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 78-90-0(Hazardous Substances Data)

Usage

Chemical Properties

clear liquid

Uses

Different sources of media describe the Uses of 78-90-0 differently. You can refer to the following data:
1. In conjunction with cupric sulfate it is a very sensitive reagent for mercury.
2. 1,2-Diaminopropane was used as model precursor in the electron induced deposition of amorphous carbon nitride films.

Definition

ChEBI: A diamine that is propane substituted by amino groups at positions 1 and 2. Propylenediamine is commonly used as a bidentate ligand in the formation of coordination complexes.

General Description

A colorless liquid with an ammonia-like odor. Flash point 160°F. Density 0.87 g / cm3. Boiling point 243°F. Strongly irritates skin and tissue.

Air & Water Reactions

Very hygroscopic. Very soluble in water.

Reactivity Profile

1,2-Diaminopropane neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Flammability and Explosibility

Flammable

Safety Profile

Moderately toxic by ingestion, sktn contact, and subcutaneous routes. A corrosive irritant to eyes, skin, and mucous membranes. Dangerous fire hazard when exposed to heat, flames, oxidizers. To fight fire, use alcohol foam. When heated to decomposition it emits toxic fumes of NOx. Used as an intermedate in production of petroleum and polymer additives, and surfactants. See also AMINES.

Purification Methods

Purify the diamine by azeotropic distillation with toluene. Then distil it. Store it in a CO2 free atmosphere. [Horton et al. Anal Chem 27 269 1955, Beilstein 4 IV 1255.]

InChI:InChI=1/C3H10N2/c1-3(5)2-4/h3H,2,4-5H2,1H3/t3-/m0/s1

Upstream product

• 17147-63-6 1-nitro-2-nitroso-propane 
• 75-55-8 2-Methylaziridine 
• 45843-05-8 (1,2-diaminopropane)2Cu(II)⁽²⁺⁾ 
• 51806-98-5 2-aminopropanenitrile 
• 4232-41-1 1,2-dinitropropane 
• 408350-46-9 β-nitro-isopropylamine 
• 78-75-1 1,2-Dibromopropane 
• 26198-63-0 1,2-Dichloropropane 
• 19777-66-3 (R)-propane-1,2-diamine dihydrochloride 
• 122833-55-0 (R)-2-Ethoxy-4-methyl-4,5-dihydro-1H-imidazole 
• 78-90-0 1,2-diaminopropan 
• 78-96-6 3-amino-2-propanol 
• 57-55-6 propylene glycol 
• 109-07-9 (RS)-2-methylpiperazine 

Downstream Products

• 122920-65-4 (R)-1.2-bis-benzamino-propane 
• 109-07-9 (RS)-2-methylpiperazine 
• 4408-81-5 1,2-diaminopropane-N,N,N',N'-tetraacetic acid 
• 89990-51-2 4-methyl-N-(1-methyl-2-{[(4-methylphenyl)sulfonyl]amino}ethyl)benzenesulfonamide 
• 72904-38-2 2,3-dihydro-2-methyl-5,6-diphenylpyrazine 
• 536753-86-3 2-methyl-dibenzo[f,h]quinoxaline 
• 78-90-0 (R)-1,2-diaminopropane 
• 19237-25-3 bis-(salicylidene)-D(-)-propylenediamine 
• 99785-05-4 N,N'-Bis-(N-benzyloxycarbonyl-glycyl)-DL-propylendiamin 
• 931-36-2 2-ethyl-4-methyl-1H-imidazole 
• 6531-31-3 4-methyl-imidazolidin-2-one 
• 2122-19-2 (rac)-4-methylimidazolidine-2-thione 
• 4538-10-7 bis-(β-amino-isopropyl)-amine 

Relevant articles and documents

Selective amination of 1,2-propanediol over Co/La3O4 catalyst prepared by liquid-phase reduction

The catalytic coupling of alcohol and ammonia is an environmentally friendly process. Cobalt-based catalysts, modified by supports (including CeO2, Fe3O4, Nb2O5, La3O4 and Al2O3), and prepared by the liquid-phase reduction, were used for the amination of 1,2-propanediol. The screened nano-Co/La3O4 catalyst exhibited an excellent catalytic performance of 68% conversion and 89% selectivity toward 2-amino-1-propanol under optimal conditions. The characterizations of the catalyst was performed by XRD, XPS, BET, TEM, TG, and CO2-TPD, revealing a relatively large specific surface area, strongly alkaline sites and a Co-La-O transition phase, which were responsible for the selective catalysis of 1,2-propanediol. The efficient construction of cobalt-based catalysts on the basis of the active species is key to improving the efficiency of the reaction process.

Method of synthesizing 2-methyltriethylenediamine with 2-methylpiperazine as raw material

The invention belongs to the field of fine chemical engineering and relates to a method of synthesizing 2-methyltriethylenediamine with 2-methylpiperazine as raw material. The method is to solve the problems of expensive and complicated raw materials and complex synthesis steps. The method can catalytically synthesize the 2-methyltriethylenediamine in one step only with the 2-methylpiperazine as araw material by means of TiO2/Pentasil zeolite as a catalyst. The method employs simple raw material, is simple and has high application value.

The invention relates to a propylene glycol and liquid ammonia as raw materials for preparing propylene diamine method and apparatus thereof

The invention relates to a method for preparing propane diamine by taking propylene glycol and liquid ammonia as raw materials. Propylene glycol and liquid ammonia are mixed in a certain ratio and are pumped into a reactor by virtue of a pump, and reaction is carried out in presence of a catalyst and hydrogen. The method for preparing the propane diamine by taking the propylene glycol and liquid ammonia as the raw materials has the advantages that a novel catalyst is adopted, catalytic performance is excellent, and long-time operation can be easily carried out; propylene glycol is subjected to hydroamination for producing a propane diamine product at lower reaction pressure, and reaction conditions are adjusted and changed, so that composition of the product can be flexibly adjusted and changed, selectivity of a target product is improved, a reaction process is simple, one-time investment of a production unit and production cost are reduced, a reaction product and a catalyst can be simply separated, and large-scale continuous industrial production can be easily realized.