- PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-IMIDAZO [2,1-B] THIAZOLE-5-SULFONYL HALIDE
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The present invention is related to the a new process for the preparation of 6-substituted-imidazo [2,1 -b] thiazole-5-sulfonyl halides of formula (I), comprising gradually adding a compound of formula (Il), into a heated solution of R1SO3H where R1 represents F or Cl, and R2 represents H, F, Cl, Br, S, (C1C6)alkyl, (C1-C6)alkoκy or triftuoromethyl.
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Page/Page column 6-7
(2009/05/28)
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- Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands
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The invention relates to compounds (I) having pharmacological activity towards the 5-HT6 receptor, and more particularly to some N-imidazo[2,1-b]thiazole-5-sulfonamide derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT6 is involved.
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Page/Page column 16; 17
(2009/12/05)
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