150433-20-8

Basic information

• Product Name: 3-(2-NAPHTHYL)PYRAZOLE
• Synonyms: BUTTPARK 23\09-56;3-(2-NAPHTHYL)PYRAZOLE;3-(2-Naphthyl)-1H-pyrazole;2-(1H-Pyrazol-3-yl)naphthalene;3-(Naphth-2-yl)-1H-pyrazole;3-(2-naphthyl)-2H-pyrazole;3-naphthalen-2-yl-2H-pyrazole;3-(naphthalen-2-yl)-1H-pyrazole
• CAS NO: 150433-20-8
• Molecular Formula: C₁₃H₁₀N₂
• Molecular Weight: 194.23
• Mol File: 150433-20-8.mol

Chemical Properties

• Melting Point: 158-159 °C(Solv: toluene (108-88-3))
• Boiling Point: 422.5±14.0 °C(Predicted)
• Appearance: /
• Density: 1.211±0.06 g/cm3(Predicted)
• PKA: 13.52±0.10(Predicted)
• CAS DataBase Reference: 3-(2-NAPHTHYL)PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-NAPHTHYL)PYRAZOLE(150433-20-8)
• EPA Substance Registry System: 3-(2-NAPHTHYL)PYRAZOLE(150433-20-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 150433-20-8(Hazardous Substances Data)

Upstream product

• 139082-65-8 3-(dimethylamino)-1-(naphthalen-2-yl)prop-2-en-1-one 
• 170859-88-8 3-(naphthalen-2-yl)prop-2-yn-1-ol 
• 93-08-3 methyl 2-naphthyl ketone 
• 652965-04-3 3-(naphthalen-2-yl)-3-oxopropanal 

Downstream Products

• 1314920-72-3 3-(naphthalen-2-yl)-1-phenyl-1H-pyrazole 

Relevant articles and documents

Synthesis, characterization and crystal structures of two 2-naphthyl substituted pyrazoles

The synthesis, characterization and X-ray crystal structures of two 2-naphthyl-substituted pyrazoles - 3-(2-naphthyl) pyrazole (1) and 5-(2-naphthyl)-3-trifluoromethyl-pyrazole (3) - are reported. In addition, the isolation and structural characterization of 5-hydroxy-3-(2-naphthyl)-5-trifluoromethyl-4,5-dihydropyrazole (2), an intermediate of the synthesis of 3, is included. Two simple methods of dehydration of 2 are also presented.

Preparation method of pyrazole derivative (by machine translation)

The preparation method comprises the following steps: mixing an alkyne propyl alcohol derivative, a halogen source, an acid and a solvent, heating and reacting, and reacting to Meyer - Schuster generate the pyrazole derivative. Compared with the prior art, the preparation method disclosed by the invention has 91% the advantages of maximum yield, simple operation, mild conditions, high conversion rate, few byproducts and the like, and provides a brand-new synthetic method for construction of pyrazole compounds. (by machine translation)

Trinuclear diamagnetic nickel(II) complexes with bridging 3-arylpyrazolato ligands

Orange-red trinuclear nickel(II) complexes are obtained by reacting Ni(ClO4)2(H2O)6 with 3(5)-arylpyrazoles in the presence of a base. Herein, the diamagnetic nickel centers are coordinated in a square-pyramidal manner by four pyrazolato ligands, each of which bridges two nickel sites. The structurally unique complexes were investigated by NMR, IR, fluorescence, and X-ray spectroscopy. All seven compounds described here were structurally elucidated by single-crystal X-ray diffraction. With 3(5)-ferrocenylpyrazole as the substrate, a nonametallic system that possesses six redox-active ferrocenyl moieties was obtained. The reactions of Ni(ClO4)2(H2O)6 with 3(5)-arylpyrazoles in the presence of a base lead to pyrazolate-bridged trinuclear nickel(II) complexes. This strategy allows the introduction of a broad variety of aromatic substituents such as redox-active sites or additional phosphine donors in the periphery of the trinuclear core. Copyright