15091-30-2

Basic information

• Product Name: 3,4-DIBROMOSULFOLANE
• Synonyms: TIMTEC-BB SBB001119;thiophene,3,4-dibromotetrahydro-,1,1-dioxide;thiophene,tetrahydro-3,4-dibromo-,1,1-dioxide;3,4-DIBROMOSULFOLANE;3,4-DIBROMOTETRAHYDROTHIOPHENE 1,1-DIOXIDE;Dibromosulfolane;3,4-DIBROMOSULFOLANE 98+%;3,4-dibromothiolane 1,1-dioxide
• CAS NO: 15091-30-2
• Molecular Formula: C₄H₆Br₂O₂S
• Molecular Weight: 277.96
• Mol File: 15091-30-2.mol

Chemical Properties

• Melting Point: 143 °C
• Boiling Point: 402.3°Cat760mmHg
• Flash Point: 197.1°C
• Appearance: /
• Density: 1.9920 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,4-DIBROMOSULFOLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIBROMOSULFOLANE(15091-30-2)
• EPA Substance Registry System: 3,4-DIBROMOSULFOLANE(15091-30-2)

Safety Data

• RTECS: XN0470000
• Hazardous Substances Data: 15091-30-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3,4-DIBROMOSULFOLANE is used as a reagent for the synthesis of pharmaceuticals, facilitating the introduction of the sulfone functional group into organic molecules, which is crucial for the development of various medicinal compounds.
Used in Agrochemical Industry:
3,4-DIBROMOSULFOLANE is used as a reagent in the synthesis of agrochemicals, where its ability to introduce the sulfone functional group is essential for creating effective agricultural products.
Used in Organic Synthesis:
3,4-DIBROMOSULFOLANE is used as a precursor for the preparation of other sulfur-containing compounds, contributing to the advancement of organic chemistry and the development of new chemical entities with potential applications in various fields.

Upstream product

• 77-79-2 3-Sulfolene 
• 15091-32-4 3,4-dibromo-tetrahydro-thiophene 

Downstream Products

• 111916-56-4 2-methyl-3β-phenyl-2,3α,3aβ,6aβ-tetrahydrothieno<2,3-d>isoxazole-4,4-dioxide 
• 111916-62-2 2,6-dimethyl-3β,5α-diphenyl-2,3α,3aβ,4aα,5β,6,7aα,7bβ-octahydrothieno<2,3-d:5,4-d'>diisoxazole-4,4-dioxide 
• 70519-79-8 3,4-diaminotetrahydrothiophene 1,1-dioxide dihydrochloride 
• 61322-63-2 4-benzylamino-2-thiolene 1,1-dioxide 
• 915186-97-9 2-amino-5a,6,8,8a-tetrahydro-4H-7λ⁶-thieno[3',4':4,5][1,3]thiazolo[3,2-a]pyrimidin-4-one 7,7-dioxide 
• 194085-44-4 (1,1-Dioxo-2,3-dihydro-1H-1λ⁶-thiophen-3-yl)-(2-iodo-phenyl)-amine 
• 17647-77-7 4-methylazulene 
• 53336-42-8 3-bromo-2,3-dihydro-thiophene-1,1-dioxide 
• 99595-59-2 3a,7a-dihydrobenzo{b}thiophene-1,1-dioxide 
• 86597-89-9 3-Phenyl-3a,6a-dihydro-thieno[2,3-d]isoxazole 4,4-dioxide 
• 86597-90-2 3,5-Diphenyl-3a,4a,7a,7b-tetrahydro-thieno[2,3-d;5,4-d']diisoxazole 4,4-dioxide 
• 86612-75-1 3,7-Diphenyl-3a,4a,7a,7b-tetrahydro-thieno[2,3-d;4,5-d']diisoxazole 4,4-dioxide 
• 77965-74-3 4,4-Dioxo-3-(2,4,6-trimethylphenyl)-3a,6a-dihydrothieno<2,3-d>isoxazoline 
• 6095-81-4 N,N'-di(2,4,6-trimethylphenyl)urea 

Relevant articles and documents

Diastereoselective Synthesis of Cyclic sp 3 -Enriched cis -β-Alkoxysulfonyl Chlorides

A three-step synthesis of β-alkoxy-substituted alicyclic sulfonyl chlorides from cyclic alkenes and alcohols is reported. The scope of the method was studied for a range of the substrates with various steric and electronic properties. The title compounds were obtained on a hundred-gram scale in up to 52% overall yield scale as single cis -diastereomers.

Synthesis of a stable 2-tributylstannyl-1,3-butadiene precursor

2-Tributylstannyl-1,3-butadiene (1) is prepared in 66% yield by retrochelotropic reaction of the corresponding sulfolene 3.

1,3-dibenzyl-4-halohexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one intermediates

Novel synthetic routes to (3aα,6aα)-1,3-dibenzyl hexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one 5,5-dioxide, a known intermediate in the synthesis of biotin are provided. A novel synthetic route from this intermediate to biotin is also disclosed.