151144-96-6

Basic information

• Product Name: L-2-AMINO-4-BROMO-4-PENTENOIC ACID
• Synonyms: L-2-AMINO-4-BROMO-4-PENTENOIC ACID;(S)-2-Amino-4-bromopent-4-enoic acid
• CAS NO: 151144-96-6
• Molecular Formula: C5H8BrNO2
• Molecular Weight: 194.03
• Product Categories: Unusual amino acids
• Mol File: 151144-96-6.mol

Chemical Properties

• Boiling Point: 279.1 °C at 760 mmHg
• Flash Point: 122.6 °C
• Appearance: /
• Density: 1.646 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.21±0.10(Predicted)
• CAS DataBase Reference: L-2-AMINO-4-BROMO-4-PENTENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: L-2-AMINO-4-BROMO-4-PENTENOIC ACID(151144-96-6)
• EPA Substance Registry System: L-2-AMINO-4-BROMO-4-PENTENOIC ACID(151144-96-6)

Safety Data

• Hazardous Substances Data: 151144-96-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
L-2-AMINO-4-BROMO-4-PENTENOIC ACID is used as a key intermediate in the synthesis of various pharmaceuticals. Its chemical structure and properties contribute to the development of potential drug candidates, facilitating the creation of new compounds with therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, L-2-AMINO-4-BROMO-4-PENTENOIC ACID serves as an essential intermediate for the production of crop protection products. Its role in the synthesis process aids in the development of effective and innovative solutions for agricultural challenges, enhancing crop yield and protection against pests and diseases.
Overall, L-2-AMINO-4-BROMO-4-PENTENOIC ACID holds significant potential in both the medical and agricultural fields, driving research and development of new compounds that address contemporary needs and challenges in these industries.

Upstream product

• 151144-95-5 (S)-2-Acetylamino-4-bromo-pent-4-enoic acid 
• 134038-94-1 diethyl 2-(2-bromoprop-2-en-1-yl)-2-acetamidopropanedioate 
• 138742-45-7 ethyl 2-acetamido-4-bromopent-4-enoate 

Downstream Products

• 151215-34-8 N-tert-butoxycarbonyl-L-2-amino-4-bromo-4-pentenoic acid 
• 119434-75-2 (S)-3-(4-thiazolyl)-2-tert-butoxycarbonylaminopropanoic acid 
• 89985-87-5 methyl (2S)-2-tert-butoxycarbonylamino-4-pentenoate 

Relevant articles and documents

Highly diastereoselective monoalkylation and Michael addition of N- (diphenylmethylene)glycinesultam under solid-liquid phase-transfer catalysis conditions using potassium carbonate as base

Treatment of a sultam-derived N-(diphenylmethylene)glycinate equivalent 1 with activated (allylic and propargylic) organic bromides and with Michael acceptors under solid-liquid phase-transfer catalysis conditions, using potassium carbonate as base, affords the monoalkylated compounds with high diastereoselectivity (>97% d.e.).

N-(Boc)-L-(2-bromoallyl)-glycine: A versatile intermediate for the synthesis of optically active unnatural amino acids

N(Boc)-L-(2-bromoallyl)-glycine (1) was synthesized from diethylacetamidomalonate and 2,3-dibromopropene in a one-pot procedure (75% overall yield). The enantiomers were efficiently separated via a tandem biocatalytic kinetic hydrolytic resolution. 1 was