151252-15-2 Usage
Uses
Used in Synthetic Organic Chemistry:
.alpha.-L-Tagatofuranose, 6-azido-6-deoxy-1,2:3,4-bis-O-(1-methylethylidene)is used as a key intermediate for the synthesis of various complex organic molecules. Its unique functional groups facilitate multiple chemical reactions, making it a versatile building block in organic synthesis.
Used in Biochemical Research:
In biochemical research, .alpha.-L-Tagatofuranose, 6-azido-6-deoxy-1,2:3,4-bis-O-(1-methylethylidene)is used as a probe to study the interactions of carbohydrates with proteins and enzymes. Its azido group allows for covalent labeling, which can help elucidate the mechanisms of carbohydrate recognition and processing.
Used in Drug Development:
.alpha.-L-Tagatofuranose, 6-azido-6-deoxy-1,2:3,4-bis-O-(1-methylethylidene)is used as a starting material for the development of new drugs targeting carbohydrate-binding proteins, which are involved in various diseases, including cancer and infectious diseases. Its unique structure enables the design of inhibitors or activators with potential therapeutic applications.
Used in Material Science:
.alpha.-L-Tagatofuranose, 6-azido-6-deoxy-1,2:3,4-bis-O-(1-methylethylidene)can be employed in the development of novel materials with specific properties, such as carbohydrate-based polymers or glycomaterials, which have applications in areas like drug delivery, sensors, and biocompatible coatings.
Used in Glycobiology and Carbohydrate Chemistry:
In the field of glycobiology and carbohydrate chemistry, .alpha.-L-Tagatofuranose, 6-azido-6-deoxy-1,2:3,4-bis-O-(1-methylethylidene)is used as a model compound to study the structure, function, and biosynthesis of carbohydrates. Its unique features can provide insights into the role of carbohydrates in biological systems and their interactions with other biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 151252-15-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,2,5 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 151252-15:
(8*1)+(7*5)+(6*1)+(5*2)+(4*5)+(3*2)+(2*1)+(1*5)=92
92 % 10 = 2
So 151252-15-2 is a valid CAS Registry Number.
151252-15-2Relevant articles and documents
Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose
Jenkinson, Sarah F.,Fleet, George W. J.,Nash, Robert J.,Koike, Yuriko,Adachi, Isao,Yoshihara, Akihide,Morimoto, Kenji,Izumori, Ken,Kato, Atsushi
, p. 4064 - 4067 (2011)
The enantiomers of tagatose are converted to l-DGJ [a noncompetitive inhibitor of human lysosome α-galactosidase A (α-Gal A), K i 38.5 μM] and DGJ [a competitive inhibitor of α-Gal A, Ki 15.1 nM] in 66% yield. l-DGJ and DGJ provide the first examples of pharmacological chaperones that (a) are enantiomeric iminosugars and (b) have synergistic activity with implications for the treatment of lysosomal storage disorders and other protein deficiencies.
Synthesis of 1,5-dideoxy-1,5-imino-D-galactitol fromL-sorbose
Furneaux, Richard H.,Tyler, Peter C.,Whitehouse, Lynley A.
, p. 3609 - 3612 (2007/10/02)
A facile new synthesis of 1-deoxygalactonojirimycin (1) [1,5-dideoxy-1,5-imino-D-galactitol] is described. The L-sorbose derivative (15) is epimerised at C-3 and converted, via the L-tagatofuranose (18) into the deoxyazide (20). Reduction of azide (20) and deprotection affords 1-deoxygalactonojirimycin (1).
