151377-80-9

Basic information

• Product Name: .alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)-
• Synonyms: .alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)-
• CAS NO: 151377-80-9
• Molecular Formula: C12H20 O6
• Molecular Weight: 260.28
• Mol File: 151377-80-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: .alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: .alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)-(151377-80-9)
• EPA Substance Registry System: .alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)-(151377-80-9)

Safety Data

• Hazardous Substances Data: 151377-80-9(Hazardous Substances Data)

Usage

General Description

.alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)- is a chemical compound that belongs to the family of furanoses. It is a derivative of tagatose, a naturally occurring sugar found in small quantities in dairy products and other foods. This specific compound is formed by the addition of two isopropylidene groups at the 1,2 and 3,4 positions of the tagatofuranose ring. These modifications alter the chemical properties of the molecule, making it useful in certain industrial applications such as the production of artificial sweeteners and pharmaceuticals. .alpha.-L-Tagatofuranose, 1,2:3,4-bis-O-(1-methylethylidene)- is also being researched for its potential as a low-calorie sweetener and its effects on blood sugar levels, making it of interest to the food and pharmaceutical industries.

Upstream product

• 41847-60-3 L-tagatose 
• 67-64-1 acetone 
• 18604-19-8 11,2:4,6-di-O-isopropylidene-α-L-sorbofuranose 
• 151377-79-6 1,2:4,6-Di-O-isopropylidene-α-L-tagatofuranose 

Downstream Products

• 151252-15-2 6-Azido-6-deoxy-1,2:3,4-di-O-isopropylidene-α-L-tagatose 
• 151252-18-5 (3aR,6S,6aR)-6-Azidomethyl-4-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ol 
• 151252-21-0 (3aS,4R,7S,7aR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridin-7-ol 

Relevant articles and documents

Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose

The enantiomers of tagatose are converted to l-DGJ [a noncompetitive inhibitor of human lysosome α-galactosidase A (α-Gal A), K i 38.5 μM] and DGJ [a competitive inhibitor of α-Gal A, Ki 15.1 nM] in 66% yield. l-DGJ and DGJ provide the first examples of pharmacological chaperones that (a) are enantiomeric iminosugars and (b) have synergistic activity with implications for the treatment of lysosomal storage disorders and other protein deficiencies.