Curcumin phosphate compound, preparation method and uses thereof
The present invention relates to a curcumin phosphate compound, a preparation method and uses thereof, and belongs to the field of pharmaceutical chemistry, wherein the structural general formula of the compound is defined in the specification, X is O or
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Paragraph 0100; 0101; 0102
(2016/10/08)
Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: A structure-activity study
We recently reported the anti-cancer and anti-cytomegalovirus (CMV) activity of artemisinin-derived trioxane diphenylphosphate dimer 838. To probe the relationship between chemical structure and anti-CMV and anti-cancer activities, we now report synthesis and evaluation of a series of eight new dimer phosphate ester analogs of 838. This series of novel molecules was screened against human foreskin fibroblasts (HFFs) infected with CMV and against the human Jurkat T cell acute lymphoblastic leukemia cell line. This SAR study confirms the very high anti-CMV and anti-cancer potencies of dimer diphenyl phosphate ester 838 without its being toxic to normal cells.
Mott, Bryan T.,He, Ran,Chen, Xiaochun,Fox, Jennifer M.,Civin, Curt I.,Arav-Boger, Ravit,Posner, Gary H.
p. 3702 - 3707
(2013/07/27)
FACTORS DETERMINING THE POSITION OF EQUILIBRIUM IN SYSTEMS OF PHOSPHORUS(III) ESTERS OR THIOESTERS AND CORRESPONDING ACID HALIDES AND HALIDITES
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Chauzov, V. A.,Studnev, Yu. N.,Ragulin, L. I.,Fokin, A. V.
p. 1146 - 1148
(2007/10/02)
Selective formation of ethanol from methanol, hydrogen and carbon monoxide
A process for the selective formation of ethanol which comprises contacting methanol, hydrogen and carbon monoxide with a catalyst system comprising cobalt acetylacetonate, a tertiary organo Group V A compound of the periodic Table, a first promoter comprising an iodine compound and a second promoter comprising a ruthenium compound.
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(2008/06/13)
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