15205-58-0Relevant academic research and scientific papers
Curcumin phosphate compound, preparation method and uses thereof
-
Paragraph 0100; 0101; 0102, (2016/10/08)
The present invention relates to a curcumin phosphate compound, a preparation method and uses thereof, and belongs to the field of pharmaceutical chemistry, wherein the structural general formula of the compound is defined in the specification, X is O or
Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: A structure-activity study
Mott, Bryan T.,He, Ran,Chen, Xiaochun,Fox, Jennifer M.,Civin, Curt I.,Arav-Boger, Ravit,Posner, Gary H.
, p. 3702 - 3707 (2013/07/27)
We recently reported the anti-cancer and anti-cytomegalovirus (CMV) activity of artemisinin-derived trioxane diphenylphosphate dimer 838. To probe the relationship between chemical structure and anti-CMV and anti-cancer activities, we now report synthesis and evaluation of a series of eight new dimer phosphate ester analogs of 838. This series of novel molecules was screened against human foreskin fibroblasts (HFFs) infected with CMV and against the human Jurkat T cell acute lymphoblastic leukemia cell line. This SAR study confirms the very high anti-CMV and anti-cancer potencies of dimer diphenyl phosphate ester 838 without its being toxic to normal cells.
Selective formation of ethanol from methanol, hydrogen and carbon monoxide
-
, (2008/06/13)
A process for the selective formation of ethanol which comprises contacting methanol, hydrogen and carbon monoxide with a catalyst system comprising cobalt acetylacetonate, a tertiary organo Group V A compound of the periodic Table, a first promoter comprising an iodine compound and a second promoter comprising a ruthenium compound.
