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2-Fluoro-6-(trifluoromethyl)benzyl alcohol is a chemical compound characterized by the molecular formula C8H6F4O. It exists as a colorless liquid with a subtle aromatic scent. 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL is distinguished by its unique structure, which includes a fluorine atom and a trifluoromethyl group attached to a benzyl alcohol moiety. Its functional groups and structural features render it a valuable intermediate in organic synthesis, especially for the production of fine chemicals and complex molecules.

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  • 152211-15-9 Structure
  • Basic information

    1. Product Name: 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL
    2. Synonyms: OTF-BYL-6F;RARECHEM AL BD 0318;[2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL]METHANOL;2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL;2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOH;2-Fluoro-6-(trifluoromethyl)benzyl alcohol 97%;2-Fluoro-6-(trifluoromethyl)benzylalcohol97%;6-fluoro-2-(trifluoromethyl)benzyl alcohol
    3. CAS NO:152211-15-9
    4. Molecular Formula: C8H6F4O
    5. Molecular Weight: 194.13
    6. EINECS: N/A
    7. Product Categories: Alcohols;C7 to C8;Oxygen Compounds;Fluorine series
    8. Mol File: 152211-15-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 180 °C(lit.)
    3. Flash Point: >230 °F
    4. Appearance: /
    5. Density: 1.397 g/mL at 25 °C(lit.)
    6. Vapor Pressure: 0.462mmHg at 25°C
    7. Refractive Index: n20/D 1.456(lit.)
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL(152211-15-9)
    12. EPA Substance Registry System: 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL(152211-15-9)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 152211-15-9(Hazardous Substances Data)

152211-15-9 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Fluoro-6-(trifluoromethyl)benzyl alcohol is utilized as a key building block in the synthesis of various pharmaceuticals and agrochemicals. Its incorporation into these compounds is attributed to its ability to enhance the biological activity and selectivity of the final products, thereby improving their efficacy and safety.
Used in Organic Synthesis:
As an important intermediate in organic synthesis, 2-Fluoro-6-(trifluoromethyl)benzyl alcohol is employed for the production of fine chemicals and complex molecules. Its unique structure and functional groups facilitate the creation of a wide range of chemical entities with diverse applications.
Used in Materials Science:
Due to the presence of fluorine atoms in its structure, 2-Fluoro-6-(trifluoromethyl)benzyl alcohol has potential applications in materials science. The properties conferred by fluorine, such as high electronegativity and strong bond strength, can be leveraged to develop new materials with improved characteristics.
Used in the Production of Fluorinated Organic Compounds:
2-Fluoro-6-(trifluoromethyl)benzyl alcohol also serves as a building block for the synthesis of fluorinated organic compounds. The introduction of fluorine atoms can significantly alter the physical, chemical, and biological properties of organic molecules, making them suitable for various specialized applications.

Check Digit Verification of cas no

The CAS Registry Mumber 152211-15-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,2,1 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 152211-15:
(8*1)+(7*5)+(6*2)+(5*2)+(4*1)+(3*1)+(2*1)+(1*5)=79
79 % 10 = 9
So 152211-15-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F4O/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-3,13H,4H2

152211-15-9 Well-known Company Product Price

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  • (Code)Product description
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  • Detail
  • Alfa Aesar

  • (B20031)  2-Fluoro-6-(trifluoromethyl)benzyl alcohol, 97%   

  • 152211-15-9

  • 1g

  • 396.0CNY

  • Detail
  • Alfa Aesar

  • (B20031)  2-Fluoro-6-(trifluoromethyl)benzyl alcohol, 97%   

  • 152211-15-9

  • 5g

  • 1486.0CNY

  • Detail

152211-15-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYL ALCOHOL

1.2 Other means of identification

Product number -
Other names [2-fluoro-6-(trifluoromethyl)phenyl]methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152211-15-9 SDS

152211-15-9Relevant articles and documents

Preparation method of Elagolix intermediate 2-fluoro-6-trifluoromethyl benzylamine

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, (2020/11/23)

The invention discloses a preparation method of an Elagolix intermediate 2-fluoro-6-trifluoromethyl benzylamine, and belongs to the technical field of medical intermediates. The preparation method comprises the following steps: (1) synthesizing 2-fluoro-6-(trifluoromethyl) benzyl alcohol; (2) synthesizing 2-fluoro-6-(trifluoromethyl) benzyl alcohol; (3) synthesizing a 2-fluoro-6-(trifluoromethyl)benzenemethanesulfonate compound and a phthalimide compound; (4) directly synthesizing a phthalimide compound; (5) synthesizing the 2-fluorine-6-trifluoromethyl benzylamine. According to the preparation method, factors such as a reaction reagent and a reaction solvent are optimized, so the reaction conditions are mild, the technological process is simple and convenient, the requirements on equipment are relatively low, the price of raw materials is lower, the purity of the obtained product is high, and industrial production is facilitated.

Method for synthesizing Elagolix midbody polysubstituted pyrimidine derivate through two-step method

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Page/Page column 6-10, (2019/06/11)

The invention discloses a method for synthesizing an Elagolix midbody polysubstituted pyrimidine derivate through a two-step method. The method comprises the following steps that (1) (2-fluoro-6-(trifluoromethyl)phenyl)methylamine shown as a formula II re

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