15232-86-7

Basic information

• Product Name: 1-heptylcyclohexene
• Synonyms: 1-Heptylcyclohexene
• CAS NO: 15232-86-7
• Molecular Formula: C₁₃H₂₄
• Molecular Weight: 180.3297
• Mol File: 15232-86-7.mol

Chemical Properties

• Boiling Point: 243.9°C at 760 mmHg
• Flash Point: 96.9°C
• Density: 0.827g/cm³
• Vapor Pressure: 0.0489mmHg at 25°C
• Refractive Index: 1.46
• CAS DataBase Reference: 1-heptylcyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-heptylcyclohexene(15232-86-7)
• EPA Substance Registry System: 1-heptylcyclohexene(15232-86-7)

Safety Data

• Hazardous Substances Data: 15232-86-7(Hazardous Substances Data)

Upstream product

• 106522-92-3 1-heptyl-3-methoxybenzene 
• 33867-02-6 1-chloromethylcyclohexene 
• 3761-92-0 n-hexylmagnesium bromide 

Relevant articles and documents

β- and γ-disubstituted olefins: Substrates for copper-catalyzed asymmetric allylic substitution

The copper-catalyzed asymmetric allylic alkylation has shown through many examples that it is a powerful means to generate stereogenic centers with mono β- and γ-substituted olefinic substrates. However, little has been reported about more substituted olefinic patterns, such as β-disubstituted allylic electrophiles. In this paper, we show that a simple procedure using easily accessible Grignard reagents and as low as 3 mol% of copper/ligand can promote high to nearly perfect enantioselectivities (up to >99% ee) with very good γ-selectivities on a wide panel of aliphatic or aromatic β-disubstituted substrates.

β-disubstituted allylic chlorides: Substrates for the Cu-catalyzed asymmetric SN2′ reaction

Scope broadened: A previously developed asymmetric Cu-catalyzed allylic substitution can be applied to more substituted allylic patterns. Two classes of β-disubstituted substrates, cinnamyl derivatives and aliphatic endocyclic allylic chlorides, afford excellent regio- and enantioselectivities (see schemes; L* = phosphoramidite ligand). (Chemical Equation Presented).

Scope and limitations of lithium-ethylenediamine-THF-mediated cleavage at the α-position of aromatics: Deprotection of aryl methyl ethers and benzyl ethers under mild conditions

The scope and limitation of lithium-ethylenediamine-THF-mediated reductive bond cleavage at the α-position of aromatics were examined. Very mild conditions such as lithium metal (5 equiv) and ethylenediamine (7 equiv) in oxygen-free THF were quite effective for the demethylation of aromatic ethers even at as low as -10°C. Allyl benzyl ethers were also deprotected under these conditions with very little change of the allylic alcohol moiety. Through this study, 2,6-dimethylbenzyl (m-xylylmethyl, MXM) group was developed as an alternative of benzyl group, which is readily cleavable under the above mentioned reductive conditions.