152559-31-4

Basic information

• Product Name: 6H-PYRAZOLO[3,4-C]PYRIDINE-6-CARBOXYLIC ACID, 1,2,3,4,5,7-HEXAHYDRO-3-OXO-, 1,1-DIMETHYLETHYL ESTER
• Synonyms: 6H-PYRAZOLO[3,4-C]PYRIDINE-6-CARBOXYLIC ACID, 1,2,3,4,5,7-HEXAHYDRO-3-OXO-, 1,1-DIMETHYLETHYL ESTER;1,2,3,4,5,7-Hexahydro-3-oxo-6H-pyrazolo[3,4-c]pyridin-6-carboxylicacidtert-butylester
• CAS NO: 152559-31-4
• Molecular Formula: C11H17N3O3
• Molecular Weight: 239.27
• Mol File: 152559-31-4.mol

Chemical Properties

• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• PKA: 11.86±0.20(Predicted)
• CAS DataBase Reference: 6H-PYRAZOLO[3,4-C]PYRIDINE-6-CARBOXYLIC ACID, 1,2,3,4,5,7-HEXAHYDRO-3-OXO-, 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-PYRAZOLO[3,4-C]PYRIDINE-6-CARBOXYLIC ACID, 1,2,3,4,5,7-HEXAHYDRO-3-OXO-, 1,1-DIMETHYLETHYL ESTER(152559-31-4)
• EPA Substance Registry System: 6H-PYRAZOLO[3,4-C]PYRIDINE-6-CARBOXYLIC ACID, 1,2,3,4,5,7-HEXAHYDRO-3-OXO-, 1,1-DIMETHYLETHYL ESTER(152559-31-4)

Safety Data

• Hazardous Substances Data: 152559-31-4(Hazardous Substances Data)

Upstream product

• 71233-25-5 ethyl 1-tert-butoxycarbonyl-3-oxopiperidine-4-carboxylate 

Downstream Products

• 1023299-85-5 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine 

Relevant articles and documents

P2X7 MODULATORS

The present invention is directed to compounds of Formulas (I, IIa and IIb): The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, IIa and IIb). Methods of making and using the compounds of Formulas (I, IIa and IIb) are also within the scope of the invention.

Palladium-catalyzed allylation of 3-hydroxyisoxazole, 5-isoxazolone and 5-pyrazolone systems

Kinetic vs. thermodynamic control and steric hindrance are factors that determine the regioselectivity of the Pd(O)-catalyzed allylation of ambident heterocycles of the 3-hydroxyisoxazole, 5-isoxazolone and 5-pyrazolone series.