152684-26-9

Basic information

• Product Name: 5-BROMO-3-METHOXY-2-NITROPYRIDINE
• Synonyms: 5-BROMO-3-METHOXY-2-NITROPYRIDINE;3-Bromo-5-methoxy-6-nitropyridine;Pyridine, 5-bromo-3-methoxy-2-nitro-
• CAS NO: 152684-26-9
• Molecular Formula: C₆H₅BrN₂O₃
• Molecular Weight: 233.0195
• EINECS: -0
• Product Categories: Pyridine
• Mol File: 152684-26-9.mol

Chemical Properties

• Melting Point: 112℃
• Boiling Point: 335℃
• Flash Point: 156℃
• Appearance: /
• Density: 1.730
• Vapor Pressure: 0.000246mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -8.84±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-3-METHOXY-2-NITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-3-METHOXY-2-NITROPYRIDINE(152684-26-9)
• EPA Substance Registry System: 5-BROMO-3-METHOXY-2-NITROPYRIDINE(152684-26-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26
• Hazardous Substances Data: 152684-26-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-BROMO-3-METHOXY-2-NITROPYRIDINE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs for the treatment of different diseases. Its unique structure allows for the creation of diverse medicinal compounds through organic synthesis.
Used in Agrochemical Industry:
In the agrochemical sector, 5-BROMO-3-METHOXY-2-NITROPYRIDINE serves as an intermediate in the production of agrochemicals, potentially enhancing crop protection and management through the development of novel pesticides and other related products.
Used in Organic Chemistry Research:
5-BROMO-3-METHOXY-2-NITROPYRIDINE is utilized as a reagent in organic chemistry, participating in a wide range of chemical reactions to form new compounds. Its presence in these reactions facilitates the exploration of novel chemical pathways and the synthesis of innovative organic molecules.
Used in Chemical Synthesis:
As a key component in chemical synthesis, 5-BROMO-3-METHOXY-2-NITROPYRIDINE is employed to create a variety of organic compounds. Its versatile nature supports the generation of new substances for applications in various fields, including but not limited to medicine, materials science, and environmental chemistry.

InChI:InChI=1/C6H5BrN2O3/c1-12-5-2-4(7)3-8-6(5)9(10)11/h2-3H,1H3

Upstream product

• 625-92-3 3,5-dibromopyridine 
• 50720-12-2 3-bromo-5-methoxypyridine 

Downstream Products

• 42409-58-5 5-bromo-3-methoxy-pyridin-2-amine 
• 1369766-55-1 (1R,2S)-2-{[(2,4-dimethylpyrimidin-5-yl)oxy]methyl}-N-(6-fluoro-5-methoxypyridin-3-yl)-2-phenylcyclopropanecarboxamide 
• 880870-66-6 5-bromo-2-fluoro-3-methoxypyridine 
• 152684-14-5 3-methylamino-2-nitro-5-phenylpyridine 
• 105650-23-5 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine 
• 152684-17-8 3-methoxy-2-nitro-5-phenylpyridine 
• 152684-19-0 3-methoxy-2-nitro-5-(3-nitrophenyl)pyridine 
• 152684-18-9 3-methoxy-5-(4-methylphenyl)-2-nitropyridine 

Relevant articles and documents

DISUBSTITUTED IMIDAZOLE DERIVATIVES AS MODULATORS OF RAF KINASE

Novel substituted imidazole compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with an additional agent f

Quinolizinone compound and use thereof as HIV integrase inhibitor

A pharmaceutical agent having an anti-HIV action, particularly, a pharmaceutical agent having an integrase inhibitory action, is provided. The present invention relates to a quinolizinone compound represented by the following formula [I] wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, and an anti-HIV agent containing same as an active ingredient. The compound of the present invention has an HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compounds can become a more effective anti-HIV agent. Since the compound has a high inhibitory activity specific for integrases, the compound can provide a safe pharmaceutical agent for human with a fewer side effects.

Synthetic Routes to Nitroamino Precursors of the Food Carcinogen 2-Amino-1-methyl-6-phenyl-1H-imidazopyridine and its 3-Methyl Isomer via Pd(0)-Catalysed Arylation

The synthesis of the novel key intermediates 3-methylamino-2-nitro- and 2-methylamino-3-nitro-5-phenylpyridine, and some of their derivatives substituted in the benzene ring, from 5-bromonicotinic acid, 3-bromo-5-methoxypyridine, 2-chloro-3-nitropyridine, 2-amino-5-bromopyridine or 5-bromo-2-methoxypyridine is described.Palladium(0)-mediated arylation of bromopyridines with areneboronic acids was an essential step in the syntheses.