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2-Chloro-3-fluoro-5-iodopyridine is a heterocyclic aromatic compound with the molecular formula C5H2ClFIN. It features a pyridine ring to which chlorine, fluorine, and iodine atoms are attached, offering unique structural and reactivity properties that make it a valuable component in various chemical applications.

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  • 153034-99-2 Structure
  • Basic information

    1. Product Name: 2-CHLORO-3-FLUORO-5-IODOPYRIDINE
    2. Synonyms: 2-CHLORO-3-FLUORO-5-IODOPYRIDINE
    3. CAS NO:153034-99-2
    4. Molecular Formula: C5H2ClFIN
    5. Molecular Weight: 257.431953
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 153034-99-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 237.216 °C at 760 mmHg
    3. Flash Point: 97.265 °C
    4. Appearance: /
    5. Density: 2.129 g/cm3
    6. Vapor Pressure: 0.07mmHg at 25°C
    7. Refractive Index: 1.614
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: -2.19±0.10(Predicted)
    11. CAS DataBase Reference: 2-CHLORO-3-FLUORO-5-IODOPYRIDINE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-CHLORO-3-FLUORO-5-IODOPYRIDINE(153034-99-2)
    13. EPA Substance Registry System: 2-CHLORO-3-FLUORO-5-IODOPYRIDINE(153034-99-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 153034-99-2(Hazardous Substances Data)

153034-99-2 Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-3-fluoro-5-iodopyridine is used as a building block and intermediate for the synthesis of pharmaceuticals. Its unique structure contributes to the development of new drugs, particularly in medicinal chemistry and drug discovery, where its reactivity can be harnessed to create novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical field, 2-Chloro-3-fluoro-5-iodopyridine serves as an essential intermediate in the production of various agrochemicals. Its incorporation into these compounds can enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Organic Synthesis:
2-Chloro-3-fluoro-5-iodopyridine is utilized as a reagent in organic synthesis, where its distinct properties allow for the creation of a wide range of organic compounds. Its versatility in this area is appreciated by synthetic chemists who seek to develop innovative materials and compounds.
Used in Chemical Research:
As a compound of interest to researchers, 2-Chloro-3-fluoro-5-iodopyridine is also used in chemical research. Its potential applications in various industries make it a valuable subject for study, with the aim of uncovering new uses and expanding the understanding of its chemical behavior.

Check Digit Verification of cas no

The CAS Registry Mumber 153034-99-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,0,3 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 153034-99:
(8*1)+(7*5)+(6*3)+(5*0)+(4*3)+(3*4)+(2*9)+(1*9)=112
112 % 10 = 2
So 153034-99-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H2ClFIN/c6-5-4(7)1-3(8)2-9-5/h1-2H

153034-99-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloro-3-fluoro-5-iodopyridine

1.2 Other means of identification

Product number -
Other names Pyridine,2-chloro-3-fluoro-5-iodo

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153034-99-2 SDS

153034-99-2Downstream Products

153034-99-2Relevant articles and documents

HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE

-

Page/Page column 88-89, (2009/10/22)

The present invention relates to compounds and methods which may be useful as inhibitors of GPR119 for the treatment or prevention of metabolic, cardiovascular, and metabolic diseases.

First Metalation of Aryl Iodides: Directed Ortho-Lithiation of Iodopyridines, Halogen-Dance, and Application to Synthesis

Rocca, P.,Cochennec, C.,Marsais, F.,Thomas-dit-Dumont, L.,Mallet, M.,et al.

, p. 7832 - 7838 (2007/10/02)

Metalation of iodopyridines was succesfully achieved by LDA at low temperature.In many cases, lithiation is ortho directed by the iodo group which subsequently ortho-migrates very fast to give stabilized iodolithiopyridines.This procedure was applied to 2

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