153390-76-2Relevant articles and documents
Solid-Phase Synthesis of Sequence-Defined Informational Oligomers
Strom, Kyle R.,Szostak, Jack W.
, p. 13929 - 13938 (2020/11/20)
Genetic biopolymers utilize defined sequences and monomer-specific molecular recognition to store and transfer information. Synthetic polymers that mimic these attributes using reversible covalent chemistry for base-pairing pose unique synthetic challenge
Induced chirality sensing through formation and aggregation of the chiral imines double winged with pyrenes or perylenes
Wu, Jianlin,Liang, Wenting,Niu, Tong,Wu, Wanhua,Zhou, Dayang,Fan, Chunying,Ji, Jiecheng,Gao, Guowei,Men, Jian,Yang, Yonggang,Yang, Cheng
, p. 9206 - 9209 (2018/08/24)
Reaction of chiral amines with benzaldehydes 3,5-disubstituted by two pyrenes or perylenes afforded corresponding double winged chiral imines, which aggregated to show significantly enhanced circular dichroism spectra at the transition bands of the chromo
Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling
Wu, Yuteng,Olsen, Lasse B.,Lau, Yu Heng,Jensen, Claus Hatt,Rossmann, Maxim,Baker, Ysobel R.,Sore, Hannah F.,Collins, Súil,Spring, David R.
, p. 689 - 692 (2016/04/26)
Photoaffinity labelling is a useful method for studying how proteins interact with ligands and biomolecules, and can help identify and characterise new targets for the development of new therapeutics. We present the design and synthesis of a novel multifunctional benzophenone linker that serves as both a photo-crosslinking motif and a peptide stapling reagent. Using double-click stapling, we attached the benzophenone to the peptide via the staple linker, rather than by modifying the peptide sequence with a photo-crosslinking amino acid. When applied to a p53-derived peptide, the resulting photoreactive stapled peptide was able to preferentially crosslink with MDM2 in the presence of competing protein. This multifunctional linker also features an extra alkyne handle for downstream applications such as pull-down assays, and can be used to investigate the target selectivity of stapled peptides.
Synthesis of valuable terpyridine building blocks to generate a variety of metallodendrons by the convergent approach
Dumur, Frédéric,Mayer, Cédric R.,Dumas, Eddy,Marrot, Jér?me,Sécheresse, Francis
, p. 4143 - 4146 (2008/02/03)
Efficient strategies for the synthesis of three building-blocks 4′-(functionalized)-2,2′:6′,2″-terpyridine have been developed for the convergent synthesis of metallodendrons; these strategies provide a practical approach for the rational design of highly
Synthesis of novel cross-conjugated dendritic fluorophores containing both phenylenevinylene and phenyleneethynylene moieties
Diez-Barra, Enrique,Garcia-Martinez, Joaquin C.,Rodriguez-Lopez, Julian
, p. 832 - 838 (2007/10/03)
New dendrons and dendrimers with dendritic arms composed of alternate phenyleneethynylene and phenylenevinylene moieties have been efficiently synthesized using orthogonal and convergent syntheses that combine Sonogashira and Horner-Wadsworth-Emmons react
Design, synthesis, and photodynamics of light-harvesting arrays comprised of a porphyrin and one, two, or eight boron-dipyrrin accessory pigments
Li, Feirong,Yang, Sung Ik,Ciringh, Yangzhen,Seth, Jyoti,Martin II, Charles H.,Singh, Deepak L.,Kim, Dongho,Birge, Robert R.,Bocian, David F.,Holten, Dewey,Lindsey, Jonathan S.
, p. 10001 - 10017 (2007/10/03)
Light-harvesting arrays containing one, two, or eight boron-dipyrrin (BDPY) pigments and one porphyrin (free base or Zn chelate) have been synthesized using a modular building block approach. The reaction of pyrrole and 4-(BDPY)benzaldehyde or 3,5-bis(BDP
New Derivatives of 4,4,5,5-Tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-Oxide as Monomers for Polyradicals with Special Magnetic Properties
Saf, Robert,Swoboda, Petra,Hummel, Klaus,Czaputa, Rainer
, p. 425 - 428 (2007/10/02)
The preparation of new derivatives of 4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide as monomers for purely organic polymers with special magnetic properties is described. 3,5-Diethynylbenzaldehyde and 3,5-bis(trimethylsilylethynyl)benzaldehyd