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2-Pyridinecarboxaldehyde,6-ethyl-(9CI), with the molecular formula C9H9NO and CAS number 6020-29-1, is an aldehyde derivative of pyridine featuring an ethyl group at the 6th position. This chemical compound serves as a versatile building block in the synthesis of a variety of organic compounds and pharmaceuticals, and it may also find applications in agrochemicals and materials science. Due to its potential hazardous properties, it is crucial to handle this compound with proper care in a controlled laboratory setting.

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  • 153646-82-3 Structure
  • Basic information

    1. Product Name: 2-Pyridinecarboxaldehyde,6-ethyl-(9CI)
    2. Synonyms: 2-Pyridinecarboxaldehyde,6-ethyl-(9CI);6-Ethylpicolinaldehyde
    3. CAS NO:153646-82-3
    4. Molecular Formula: C8H9NO
    5. Molecular Weight: 135.16316
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 153646-82-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 205.4±28.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.063±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. PKA: 3.93±0.10(Predicted)
    10. CAS DataBase Reference: 2-Pyridinecarboxaldehyde,6-ethyl-(9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-Pyridinecarboxaldehyde,6-ethyl-(9CI)(153646-82-3)
    12. EPA Substance Registry System: 2-Pyridinecarboxaldehyde,6-ethyl-(9CI)(153646-82-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 153646-82-3(Hazardous Substances Data)

153646-82-3 Usage

Uses

Used in Pharmaceutical Industry:
2-Pyridinecarboxaldehyde,6-ethyl-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Pyridinecarboxaldehyde,6-ethyl-(9CI) is utilized as a precursor in the creation of compounds that can be applied in pest control and crop protection, leveraging its chemical structure to target specific pests or enhance plant resistance.
Used in Materials Science:
2-Pyridinecarboxaldehyde,6-ethyl-(9CI) is employed as a component in the development of new materials, potentially contributing to advancements in areas such as polymer science, where its unique structure may impart specific properties to the resulting materials.

Check Digit Verification of cas no

The CAS Registry Mumber 153646-82-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,6,4 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 153646-82:
(8*1)+(7*5)+(6*3)+(5*6)+(4*4)+(3*6)+(2*8)+(1*2)=143
143 % 10 = 3
So 153646-82-3 is a valid CAS Registry Number.

153646-82-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-ethylpyridine-2-carbaldehyde

1.2 Other means of identification

Product number -
Other names 6-ethylpyridine-2-carboxaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153646-82-3 SDS

153646-82-3Relevant articles and documents

Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy

Kempf, Dale J.,Sham, Hing L.,Marsh, Kennan C.,Flentge, Charles A.,Betebenner, David,Green, Brian E.,McDonald, Edith,Vasavanonda, Sudthida,Saldivar, Ayda,Wideburg, Norman E.,Kati, Warren M.,Ruiz, Lisa,Zhao, Chen,Fino, Lynnmarie,Patterson, Jean,Molla, Akhteruzzaman,Plattner, Jacob J.,Norbeck, Daniel W.

, p. 602 - 617 (2007/10/03)

The structure-activity studies leading to the potent and clinically efficacious HIV protease inhibitor ritonavir are described. Beginning with the moderately potent and orally bioavailable inhibitor A-80987, systematic investigation of peripheral (P3 and P2') heterocyclic groups designed to decrease the rate of hepatic metabolism provided analogues with improved pharmacokinetic properties after oral dosing in rats. Replacement of pyridyl groups with thiazoles provided increased chemical stability toward oxidation while maintaining sufficient aqueous solubility for oral absorption. Optimization of hydrophobic interactions with the HIV protease active site produced ritonavir, with excellent in vitro potency (EC50 = 0.02 μM) and high and sustained plasma concentrations after oral administration in four species. Details of the discovery and preclinical development of ritonavir are described.

PYRIDINE-SUBSTITUTED BENZYL ALCOHOLS AS LEUKOTRIENE ANTAGONISTS

-

, (2008/06/13)

Compounds having the formula I: STR1 are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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