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4-IODONICOTINIC ACID, also known as 4-iodopyridine-3-carboxylic acid, is an organic compound characterized by the chemical formula C6H4INO2. It is a derivative of nicotinic acid, featuring an iodine atom attached to the fourth position of the pyridine ring. This white to light brown crystalline powder is slightly soluble in water and soluble in organic solvents, making it a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also an important building block in organic synthesis, with potential applications in the development of new drugs and the manufacturing of agricultural chemicals.

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  • 15366-63-9 Structure
  • Basic information

    1. Product Name: 4-IODONICOTINIC ACID
    2. Synonyms: 4-IODOPYRIDINE-3-CARBOXYLIC ACID;4-IODONICOTINIC ACID
    3. CAS NO:15366-63-9
    4. Molecular Formula: C6H4INO2
    5. Molecular Weight: 249.01
    6. EINECS: N/A
    7. Product Categories: Pyridines
    8. Mol File: 15366-63-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 350 °C at 760 mmHg
    3. Flash Point: 165.5 °C
    4. Appearance: /
    5. Density: 2.123 g/cm3
    6. Vapor Pressure: 1.69E-05mmHg at 25°C
    7. Refractive Index: 1.677
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 0.86±0.10(Predicted)
    11. CAS DataBase Reference: 4-IODONICOTINIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-IODONICOTINIC ACID(15366-63-9)
    13. EPA Substance Registry System: 4-IODONICOTINIC ACID(15366-63-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 15366-63-9(Hazardous Substances Data)

15366-63-9 Usage

Uses

Used in Pharmaceutical Industry:
4-IODONICOTINIC ACID is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs that can address a range of health conditions.
Used in Agrochemical Industry:
4-IODONICOTINIC ACID is used as a precursor in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and agricultural productivity.
Used in Organic Synthesis:
4-IODONICOTINIC ACID is utilized as a building block in organic synthesis, enabling the construction of complex organic compounds for a variety of applications, including the development of new materials and chemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 15366-63-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,3,6 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15366-63:
(7*1)+(6*5)+(5*3)+(4*6)+(3*6)+(2*6)+(1*3)=109
109 % 10 = 9
So 15366-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H4INO2/c7-5-1-2-8-3-4(5)6(9)10/h1-3H,(H,9,10)

15366-63-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Iodopyridine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 4-Iodnicotinsaeure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15366-63-9 SDS

15366-63-9Upstream product

15366-63-9Downstream Products

15366-63-9Relevant articles and documents

Directed lithiation of unprotected pyridinecarboxylic acids: Syntheses of halo derivatives

Lazaar, Jalal,Rebstock, Anne-Sophie,Mongin, Florence,Godard, Alain,Trécourt, Fran?ois,Marsais, Francis,Quéguiner, Guy

, p. 6723 - 6728 (2007/10/03)

Deprotonation of all isomeric lithium pyridinecarboxylates and subsequent trapping with hexachloroethane or iodine afforded straightforward access to chloro- and iodopyridinecarboxylic acids, respectively. Starting from lithium 5-bromonicotinate, the introduction of an iodine atom at C4 and further halogen migration allowed the potential of this method to be extended to the synthesis of more elaborate derivatives.

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