1537892-36-6 Usage
Uses
Used in Bioconjugation:
Mal-PEG3-NHS ester is used as a bioconjugation agent for the attachment of proteins, oligonucleotides, and other amine-containing molecules to biomolecules with a thiol group. This application is crucial for the development of various biotechnological and pharmaceutical products, as it allows for the creation of stable and functional conjugates.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Mal-PEG3-NHS ester is used as a component in drug delivery systems. The ability to form covalent bonds with thiol-containing drug molecules enhances the stability and solubility of the drug, potentially improving its bioavailability and therapeutic efficacy.
Used in Diagnostic Tools:
Mal-PEG3-NHS ester is also utilized in the development of diagnostic tools. Its labeling capabilities allow for the attachment of detection markers or signaling molecules to biomolecules, which can be useful in assays, sensors, and imaging techniques.
Used in Research and Development:
In the field of research, Mal-PEG3-NHS ester serves as a valuable reagent for the creation of novel bioconjugates and the study of molecular interactions. Its versatility in linking different types of molecules makes it a popular choice for exploring new biological pathways and mechanisms.
Overall, Mal-PEG3-NHS ester is a versatile and valuable molecule in the fields of biotechnology, pharmaceuticals, diagnostics, and research, due to its ability to enhance solubility, facilitate bioconjugation, and improve the stability and efficacy of various biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1537892-36-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,3,7,8,9 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1537892-36:
(9*1)+(8*5)+(7*3)+(6*7)+(5*8)+(4*9)+(3*2)+(2*3)+(1*6)=206
206 % 10 = 6
So 1537892-36-6 is a valid CAS Registry Number.
1537892-36-6Relevant articles and documents
CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME
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Page/Page column 98, (2016/04/09)
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES
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Page/Page column 119, (2015/07/15)
Sulfonamide-containing linkage systems for release of payload compounds from an attached targeting moiety in drug conjugates. The conjugates have the formula of [(P)-(L)]m-(T), wherein (P) is a payload compound, (L) is a linker, (T) is a targeting moiety and m is an integer from 1- to 10. Also provided are pharmaceutical compositions comprising such conjugates and there use in treating cancer.
