154549-38-9

Basic information

• Product Name: 2,4,6-TRIISOPROPYLBENZENEBORONIC ACID
• Synonyms: 2,4,6-TRIISOPROPYLBENZENEBORONIC ACID;2,4,6-Triisopropylphenylboronic Acid (contains varying amounts of Anhydride);(2,4,6-Triisopropylphenyl)boronic acid 2,4,6-Triisopropylphenylboronic acid
• CAS NO: 154549-38-9
• Molecular Formula: C₁₅H₂₅BO₂
• Molecular Weight: 248.17
• Product Categories: Trisubstituted Aryl Boronic Acids;Aryl Boronic Acids;Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Organometallic Reagents
• Mol File: 154549-38-9.mol

Chemical Properties

• Melting Point: 165°C
• Boiling Point: 346.8°Cat760mmHg
• Flash Point: 163.5°C
• Appearance: /
• Density: 0.97g/cm³
• Vapor Pressure: 2.12E-05mmHg at 25°C
• Refractive Index: 1.498
• Storage Temp.: 2-8°C
• Solubility: soluble in Acetone
• PKA: 9.04±0.58(Predicted)
• CAS DataBase Reference: 2,4,6-TRIISOPROPYLBENZENEBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIISOPROPYLBENZENEBORONIC ACID(154549-38-9)
• EPA Substance Registry System: 2,4,6-TRIISOPROPYLBENZENEBORONIC ACID(154549-38-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• TSCA: No
• Hazardous Substances Data: 154549-38-9(Hazardous Substances Data)

Usage

Uses

2,4,6-TRIISOPROPYLBENZENEBORONIC ACID is a useful research chemical.

InChI:InChI=1/C15H25BO2/c1-9(2)12-7-13(10(3)4)15(16(17)18)14(8-12)11(5)6/h7-11,17-18H,1-6H3

Upstream product

• 21524-34-5 2,4,6-triisopropyl-1-bromobenzene 

Downstream Products

• 335343-07-2 dibutyl 2,4,6-triisopropylphenylboronate 
• 1246888-92-5 3-(2,4,6-triisopropylphenyl)pyridine 
• 1391976-76-3 (C₅H₄N)N(CH₃)(CH₂)6(C₆H₃O₂B)(2,4,6-C₆H₂iPr₃) 
• 1391976-79-6 2-(2,4,6-triisopropylphenyl)-1,3,2-benzodioxaborole 
• 1394213-93-4 (E)-3-(2,4,6-triisopropylphenyl)allyl acetate 
• 1394213-82-1 (E)-2-(hexa-1,5-dienyl)-1,3,5-triisopropylbenzene 
• 1408055-36-6 (R)-N-(1-phenylethyl)-6-(2,4,6-tri-isopropylphenyl)thieno[2,3-d]pyrimidin-4-amine 
• 1416065-69-4 2-(N-phenylamino)-3-(N-isopropylamino)-6-(2',4',6'-triisopropylphenyl)pyridine 
• 1263064-84-1 1-(2,4,6-triisopropylphenyl)-2-methylnaphthalene 
• 1428318-93-7 (R,R)-bis(5-triisopropylbenzene-3-tert-butylsalicylidene)-1,2-cyclohexanediamine 
• 1433897-26-7 6-(2,4,6-triisopropylphenyl)-2-pyridinecarboxaldehyde 
• 1433897-00-7 C₅₀H₆₂N₄ 
• 1433897-62-1 C₆₆H₈₆N₄Ni₂ 
• 10330-42-4 1-fluoro-2,4,6-triisopropylbenzene 

Relevant articles and documents

2,6-diisopropyl benzene boric acid derivatives an pharmaceutical use thereof

The invention relates to a type of 2,6-diisopropyl benzene boric acid derivatives and pharmaceutical use thereof. The structure of the derivatives is accordant with a general formula shown in the description, wherein R1 represents -H or -CH(CH3)2. The drugs are sensitive to free radicals, and a large number of free radicals exist at ischemic parts, so that the drugs are capable of releasing diprivan or analogs of diprivan at the ischemic parts, are capable of well protecting ischemic injury and have a neuroprotective effect better than that of diprivan. The derivatives can be applied to the preparation of drugs for treating the ischemic injury.

Suzuki cross-coupling reaction of sterically hindered aryl boronates with 3-iodo-4-methoxybenzoic acid methylester

The cross-coupling reaction of 3-iodo-4-methoxybenzoic acid methylester with sterically hindered arylboronic esters and especially 5,5-dimethyl-2-mesityl-1,3,2-dioxaborinane, is reported. The optimisation of the process in order to obtain biaryls in good yield by using anhydrous benzene at reflux and sodium phenoxide in the presence of 0.06 equiv. of Pd(PPh3)4 is described. (C) 2000 Elsevier Science Ltd.